Results 111 to 120 of about 9,409,602 (307)

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

The effects of short-term use of granulocyte colony-stimulating factor on bone metabolism in child cancer patients

İstanbul Kuzey Klinikleri, 2018
INTRODUCTION[|]The granulocyte colony-stimulating factor (G-CSF) is the most commonly used hematopoietic growth factor recombinant DNA technology. It affects bone metabolism by modulating both osteoclast and osteoblast functions.
Ayse Bozkurt Turhan, Cigdem Binay, Ozcan Bor, Enver Simsek   +3 more
doaj   +1 more source

Disruption of embryonic blood-CSF barrier in chick embryos reveals the actual importance of this barrier to control E-CSF composition and homeostasis in early brain development

, 2013
In vertebrates, early brain development takes place at the expanded anterior end of the neural tube. After closure of the anterior neuropore, the brain wall forms a physiologically sealed cavity that encloses embryonic cerebrospinal fluid (E-CSF), a ...
Bueno i Torrens, David, 1965-, Parvas, Maryam   +1 more
core  

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

G-CSF associates with neurogenesis and predicts prognosis and sensitivity to chemotherapy in pancreatic ductal adenocarcinoma

, 2018
Lingfu Zhang,1 Lianyuan Tao,1 Limei Guo,2 Jun Zhan,3 Chunhui Yuan,1 Zhaolai Ma,1 Bin Jiang,1 Dianrong Xiu1 1Department of General Surgery, Peking University Third Hospital, Beijing, People’s Republic of China; 2Department of Pathology, Peking ...
Yuan C, Xiu D, Guo L, Tao L, Jiang B, Ma Z, Zhang L, Zhan J   +7 more
core  

The receptor for Granulocyte-colony stimulating factor (G-CSF) is expressed in radial glia during development of the nervous system-4

, 2011
Omite, E12 tongue, E16 cerebral artery, E16 cervical dorsal root ganglia, E16 tongue, E16 eye, E19 kidney, E19 intestine, (Immunohistochemical staining of 10 μm paraffin sections, scale bar 50 μm, drg: dorsal root ganglia, E: embryonic day)Copyright ...
Armin Schneider (66478), Carola Krüger (66481), Friederike Kirsch (91001)   +2 more
core   +1 more source

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper, Annaliis Lehto, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Vogt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Anja Schneider, Stefan Teipel, Johannes Prudlo, Andreas Hermann   +25 more
wiley   +1 more source

Cotreatment with Darbepoetin and Granulocyte Colony-Stimulating Factor is Efficient to Recruit Proangiogenic Cell Populations in Patients with Acute Myocardial Infarction

Cell Transplantation, 2012
To determine whether newer combination cytokine treatment with granulocyte colony-stimulating factor (G-CSF) and darbepoetin can improve efficacy of stem cell therapy, we evaluated safety and peripheral blood stem/progenitor cell (PBSC) mobilizing ...
Hyun-Jae Kang, Eun-Jung Yoon, Eun-Ju Lee, Min-Kyung Kim, Jung-Won Suh, Kyung-Woo Park, Hae-Young Lee, Kyoung Un Park, Young-Seok Cho, Bon-Kwon Koo, In-Ho Chae, Dong-Ju Choi, Kyu-Sup Han, Hyo-Soo Kim, Young-Bae Park   +14 more
doaj   +1 more source

Lack of effect of the human GM-CSF analog E21R on the survival of primary human acute myeloid leukemia cells

, 2004
The granulocyte-macrophage colony-stimulating factor (GM-CSF) analog E21R binds to the GM-CSF receptor complex with low affinity and acts as a competitive antagonist.
Jakupovic, I., Khwaja, A., Grandage, V.L., Linch, D.C.   +3 more
core  

The receptor for Granulocyte-colony stimulating factor (G-CSF) is expressed in radial glia during development of the nervous system-0

, 2011
Omite, E12 tongue, E16 cerebral artery, E16 cervical dorsal root ganglia, E16 tongue, E16 eye, E19 kidney, E19 intestine, (Immunohistochemical staining of 10 μm paraffin sections, scale bar 50 μm, drg: dorsal root ganglia, E: embryonic day)Copyright ...
Armin Schneider (66478), Carola Krüger (66481), Friederike Kirsch (91001)   +2 more
core   +1 more source