Results 101 to 110 of about 9,409,602 (307)

The embryonic blood-CSF barrier has molecular elements for specific glucose transport and for the general transport of molecules via transcellular routes.

open access: yes, 2010
In vertebrates, early brain development takes place at the expanded anterior end of the neural tube, which is filled with embryonic cerebrospinal fluid (E-CSF).
Bueno i Torrens, David, 1965-   +3 more
core   +1 more source

Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke   +5 more
wiley   +1 more source

Granulocyte colony-stimulating factor and leukemogenesis

open access: yesMediators of Inflammation, 2004
THE granulocyte colony-stimulating factor (G-CSF) plays an important role in normal granulopoiesis. Its functions are mediated by specific receptors on the surface of responsive cells and, upon ligand binding, several cytoplasmic tyrosine kinases are ...
Lorena Lobo de Figueiredo   +2 more
doaj   +1 more source

Recognition of handwritten digits by features and a multi-layer perceptron

open access: yes, 1992
International audienceHandwritten digit recognition was one of the first areas in which neural network technology was applied. Thomson-CSF/LER has developed an intermediate approach between classical methods, based on extracting small sets of parameters,
Pottier, Isabelle, Burel, Gilles
core  

Structure of Met-G-CSF.

open access: yes, 2013
A) Three-dimensional structure of Met-G-CSF (PDB ID: 1GNC) also showing (see arrows) the PEG conjugation sites of Met-G-CSF-Met1-PEG and Met-G-CSF-Gln135-PEG, which respectively are on N-terminal methionine and on glutamine 135 residue. B) Sodium dodecyl
Silvia Scaramuzza (312347)   +8 more
core   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub   +24 more
wiley   +1 more source

The role of the granulocyte colony-stimulating factor receptor (G-CSF-R) in disease

open access: yes, 2007
Granulocyte colony-stimulating factor (G-CSF) is a key regulator of granulopoiesis via stimulation of a specific cell-surface receptor, the G-CSF-R, found on hematopoietic progenitor cells as well as neutrophilic granulocytes.
Alister Ward (13059717)
core  

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez   +10 more
wiley   +1 more source

Serum G-CSF May Be a More Valuable Biomarker than Image Evaluation in G-CSF-Producing Urothelial Carcinoma: A Case Report

open access: yesCase Reports in Oncology, 2017
Granulocyte colony-stimulating factor (G-CSF)-producing urothelial carcinomas (UCs) are rare and have a poor prognosis. According to the literature, treatment for G-CSF-producing UCs is very difficult.
Kento Morozumi   +4 more
doaj   +1 more source

The receptor for Granulocyte-colony stimulating factor (G-CSF) is expressed in radial glia during development of the nervous system-2

open access: yes, 2011
spinal cord with dorsal root ganglion, axon root and muscle, E14 hindbrain, E16 spinal cord with dorsal root ganglion, E19 spinal cord, E19 spinal cord, E19 hindbrain, E21 olfactory bulb, E21 diencephalon, (Immunohistochemical staining of 10 μm paraffin ...
Armin Schneider (66478)   +2 more
core   +1 more source

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