Results 121 to 130 of about 12,166,273 (260)

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

Advanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão, Susana Simões, Paulo Rodrigues‐Santos, Vitor Francisco, Akhilesh Rai, Lino Ferreira   +5 more
wiley   +1 more source

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

Advanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte, Benjamin E. Nachod, Julia Baena, Jenna Muscat‐Rivera, Lesley Chaboub, Hannah C. Safford, Hannah C. Geisler, Hannah M. Yamagata, Melgious J. Y. Ang, Michael Kegel, Alexandre Poirier, Elaine R. Tong, Zhe Zhong, Qiangqiang Shi, Jinjin Wang, Elisa Battistini, Ye Zeng, Alex G. Hamilton, Kelsey L. Swingle, Drew Weissman, Jilian R. Melamed, Michael J. Mitchell   +21 more
wiley   +1 more source

The receptor for Granulocyte-colony stimulating factor (G-CSF) is expressed in radial glia during development of the nervous system-2

, 2011
spinal cord with dorsal root ganglion, axon root and muscle, E14 hindbrain, E16 spinal cord with dorsal root ganglion, E19 spinal cord, E19 spinal cord, E19 hindbrain, E21 olfactory bulb, E21 diencephalon, (Immunohistochemical staining of 10 μm paraffin ...
Armin Schneider (66478), Carola Krüger (66481), Friederike Kirsch (91001)   +2 more
core   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

The receptor for Granulocyte-colony stimulating factor (G-CSF) is expressed in radial glia during development of the nervous system-0

, 2011
Omite, E12 tongue, E16 cerebral artery, E16 cervical dorsal root ganglia, E16 tongue, E16 eye, E19 kidney, E19 intestine, (Immunohistochemical staining of 10 μm paraffin sections, scale bar 50 μm, drg: dorsal root ganglia, E: embryonic day)Copyright ...
Armin Schneider (66478), Carola Krüger (66481), Friederike Kirsch (91001)   +2 more
core   +1 more source

Sustainable and Multifunctional Natural Macromolecular Polymers for Aqueous Zn Metal Batteries

Advanced Materials, EarlyView.
We comprehensively review the structure‐function relationships and regulatory mechanism of natural macromolecular polymers in stabilizing zinc anodes at the microscopic and mesoscopic scales. The interactions among polymer structures, optimization strategies, and regulatory mechanisms are discussed systematically summarizing recent related research ...
Yunuo Shi, Bo Jiang, Jingcheng Zhang, Xiaodong Shao, Peixun Xiong, Lutong Shan, Shengyang Huang, Mengfang Liang, Mengyao Chang, Fangyan Liu, Wenwu Li, Baoyu Xia, Wei Ji, Ho Seok Park   +13 more
wiley   +1 more source

The receptor for Granulocyte-colony stimulating factor (G-CSF) is expressed in radial glia during development of the nervous system-4

, 2011
Omite, E12 tongue, E16 cerebral artery, E16 cervical dorsal root ganglia, E16 tongue, E16 eye, E19 kidney, E19 intestine, (Immunohistochemical staining of 10 μm paraffin sections, scale bar 50 μm, drg: dorsal root ganglia, E: embryonic day)Copyright ...
Armin Schneider (66478), Carola Krüger (66481), Friederike Kirsch (91001)   +2 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Corrigendum to “Stem Cell Mobilization with G-CSF versus Cyclophosphamide plus G-CSF in Mexican Children”

Stem Cells International, 2016
José Eugenio Vázquez Meraz, José Arellano-Galindo, Armando Martínez Avalos, Emma Mendoza-García, Elva Jiménez-Hernández   +4 more
doaj   +1 more source