Results 81 to 90 of about 310,082 (306)

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Efficacy and Toxicity of Cytarabine + G-CSF, Cyclophosphamide + G-CSF, and Plerixafor + G-CSF Mobilization of Autologous Hematopoietic Stem Cells in Hematologic Malignancy Patients with Predicted Poor Collection

Клиническая онкогематология
AIM. To compare the efficacy and toxicity of various regimens of autologous hematopoietic stem cell (HSC) mobilization (cytarabine + G-CSF, cyclophosphamide + G-CSF, and plerixafor + G-CSF) in hematologic malignancy patients with predicted poor HSC ...
Svetlana Sergeevna Elkhova, L. V. Filatova, I. S. Zyuzgin, S. A. Volchenkov, L. A. Kramynin, T. Yu. Semiglazova   +5 more
doaj   +1 more source

Cost analysis of a randomized stem cell mobilization study in multiple myeloma [PDF]

, 2016
Upfront autologous stem cell transplantation (ASCT) is the standard therapy for younger multiple myeloma (MM) patients. MM patients usually undergo stem cell mobilization with cyclophosphamide (CY) followed by granulocyte colony-stimulating factor (G-CSF)
Ahonen, Jouni, Anttila, Pekka, Jantunen, Esa, Mahlamaki, Eija, Mantymaa, Pentti, Putkonen, Mervi, Remes, Kari, Saily, Marjaana, Sankelo, Marja, Savolainen, Eeva-Riitta, Silvennoinen, Raija, Varmavuo, Ville   +11 more
core   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

Biosimilar G-CSF versus filgrastim and lenograstim in healthy unrelated volunteer hematopoietic stem cell donors [PDF]

, 2017
The World Marrow Donor Organization recommends original granulocyte-colony stimulating factor (G-CSF) for the mobilization of stem cells in healthy unrelated hematopoietic stem cell donors. We report the comparison of a biosimilar G-CSF (Zarzio) with two
Bogusz, K, Farhan, R, Krol, M, Krol, M, Piotrowska, I, Skwierawska, K, Snarski, E, Torosian, T, Urbanowska, E, Wiktor-Jedrzejczak, W, Zborowska, H   +10 more
core   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

Mobilization of healthy donors with plerixafor affects the cellular composition of T-cell receptor (TCR)-αβ/CD19-depleted haploidentical stem cell grafts [PDF]

, 2014
Background: HLA-haploidentical hematopoietic stem cell transplantation (HSCT) is suitable for patients lacking related or unrelated HLA-matched donors. Herein, we investigated whether plerixafor (MZ), as an adjunct to G-CSF, facilitated the collection of
A Bachem, A Bertaina, A Dar, A Dzionek, A Hansel, A Lundqvist, A Whitby, Alice Bertaina, AP Nademanee, AW Hauge, B Foley, B Gaugler, Barbarella Lucarelli, EK Waller, Elia Girolami, EM Sloand, ES Morris, F Locatelli, F Locatelli, F Sallusto, Franco Locatelli, G Bonanno, G Nizzoli, Gianpiero Conflitti, Giuseppina Li Pira, GL Uy, H Kared, J Cros, J Storek, JF DiPersio, JF DiPersio, JP Levesque, K Schakel, K Sunami, KP MacDonald, L Pan, L Pierelli, L Ziegler-Heitbrock, L Ziegler-Heitbrock, LB To, Letizia P Brescia, Lidia Altomare, LO Gerlach, Lorenzo Moretta, M Arpinati, M Arpinati, M Della Chiesa, M Frankenberger, M Schumm, Maria Giuseppina Cefalo, MF Martelli, P Anderlini, Perla Filippini, RM Steinman, S Rutella, S Rutella, S Rutella, S Rutella, S Rutella, Sergio Rutella, SH Baumeister, SL Jongbloed, SM Devine, SM Jackson, Stefano Ceccarelli, T Neumann, Tiziana Corsetti, U Hainz, V Reddy, Valentina Bertaina   +69 more
core   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Granulocyte Colony-stimulating Factor Supports Liver Regeneration in a Small-for-size Liver Remnant Mouse Model [PDF]

, 2018
Experimental partial hepatectomy of more than 80% of the liver weight bears an increased mortality in rodents, due to impaired hepatic regeneration in small-for-size liver remnants.
Beldi, Guido, Bisch-Knaden, Sonja, Candinas, Daniel, Gloor, Beat, Inderbitzin, Daniel, Kappeler, Andreas, Keogh, Adrian, Sidler, Daniel, Studer, Peter, Weimann, Rosy   +9 more
core  

The potential role of G-CSF in stroke [PDF]

, 2009
O fator estimulador de colônias granulocitárias (G-CSF) é uma glicoproteína descrita há mais de vinte anos, e é largamente utilizada para tratamento de estados neutropênicos e no transplante de medula óssea. O G-CSF estimula células-tronco hematopoéticas
GRECO, Oswaldo T., LAGO, Mario, MASET, Angelo L., PIRON-RUIZ, Lilian, POLONI, Alana F. C., RUIZ, Milton A.   +5 more
core   +1 more source