Results 81 to 90 of about 9,409,602 (307)

Granulocyte Colony-Stimulating Factor and Its Potential Application for Skeletal Muscle Repair and Regeneration

Mediators of Inflammation, 2017
Granulocyte colony-stimulating factor (G-CSF) was originally discovered in the context of hematopoiesis. However, the identification of the G-CSF receptor (G-CSFR) being expressed outside the hematopoietic system has revealed wider roles for G-CSF ...
Craig R. Wright, Alister C. Ward, Aaron P. Russell   +2 more
doaj   +1 more source

Revisiting G-CSF Support for Hematologic Recovery after Autologous Transplantation in AML Patients

, 2017
In acute myeloid leukemia (AML) patients, using granulocyte colony-stimulating factor (G-CSF) to support hematologic recovery in induction and consolidation treatment reduces the number of febrile episodes and the duration of neutropenia and ...
Oberson, JS, Baerlocher, Gabriela M., Pabst, Thomas, Zimmerli, Stefan, Leibundgut, Kurt, Seipel, Katja, Mansouri Taleghani, Behrouz, Novak, Urban, Mueller, BU   +8 more
core   +1 more source

G-CSF and GM-CSF Modify Neutrophil Functions at Concentrations found in Cystic Fibrosis. [PDF]

, 2019
The role of colony stimulating factors (CSFs) in cystic fibrosis (CF) circulating neutrophils has not been thoroughly evaluated, considering that the neutrophil burden of lung inflammation in these subjects is very high.
Diana A., Vinella A., De Venuto D, Leonetti G, De Venuto D., Montemurro P, Polizzi A. M., Guerra L, D'Oria S, Mariggiò MA, D'Oria S., Castellani S, Gallo C, Montemurro P., Castellani S., Mariggio M. A., Favia M, Guerra L., Leonetti G., Diana A, Di Gioia S, Favia M., Gallo C., Conese M., Polizzi AM, Vinella A, Di Gioia S.   +26 more
core   +1 more source

Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes

, 2022
Art. 747, 14 S.Ceramides are sphingolipids with defined acyl chain lengths, which are produced by corresponding ceramide synthases (CerS1-6). In experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), the ablation of ...
Blum, L., Schiffmann, S., Ulshöfer, T., Wegner, M.-S., Roser, L., Barthelmes, J., Ferreiros, N., Geisslinger, G., Kurz, J., Grösch, S.   +9 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Hemopoietic stem-cell harvesting and transplantation using G-CSF-primed BM: comparison with unprimed BM and G-CSF-primed PBSC

, 1999
Background: PBSC collected following G-CSF priming lead to more rapid hemopoietic reconstitution (HR) after autologous transplantation than do unprimed BMstem cells.
Kotlovsky, N (15484130), Scott Ragg (14747422), Deirdre Tuck (14751394), Luck, J (15484127), Parker, N (15478865), Rees, B (15484124), Raymond Lowenthal (14742817), Tegg, EM (15484121), Marsden, KA (15478868)   +8 more
core  

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

O G-CSF na terapia do acidente vascular cerebral The potential role of G-CSF in stroke

Revista Brasileira de Hematologia e Hemoterapia, 2009
O fator estimulador de colônias granulocitárias (G-CSF) é uma glicoproteína descrita há mais de vinte anos, e é largamente utilizada para tratamento de estados neutropênicos e no transplante de medula óssea. O G-CSF estimula células-tronco hematopoéticas
Angelo L. Maset, Lilian Piron-Ruiz, Oswaldo T. Greco, Mario Lago, Alana F. C. Poloni, Milton A. Ruiz   +5 more
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