Results 121 to 130 of about 24,482,117 (243)

Modelo G-DINA aplicado al diagnóstico de desórdenes mentales

open access: yes, 2019
Actualmente, uno de los modelos de diagnóstico cognitivo (MDC) más usados es el modelo DINA. Sin embargo, este modelo presenta varias restricciones que hacen que en muchas ocasiones, no sea el que mejor se ajusta a la realidad.
Villena Guzmán, Denisse
core  

GH172 Difructose Dianhydride I Synthase: A Two‐Stepped Journey via Glycosylation and Cyclization Using QM/MM Metadynamics

open access: yesChemistry – A European Journal, EarlyView.
Unlocking the chemistry of caramel by simulations and experimental validation. αFFase1${\alpha }\rm{FFase1}$ converts inulobiose into difructose dianhydride I, one component of caramel, through two steps: a rate‐limiting glycosylation (with a rare sugar ring flip) followed by a cyclization step, guided by residues E85, K147, and N226.
Santiago Alonso‐Gil   +7 more
wiley   +1 more source

Chiral Dipicolinamide‐Based Push–Pull π‐Conjugated Systems as Nonreciprocal Circularly Polarized Luminescence Emitters

open access: yesChemistry – A European Journal, EarlyView.
This work presents the synthesis and characterization of chiral dipicolinamide push–pull fluorophores. While possessing similar photophysical properties in solution, their solvent‐annealed thin films exhibit unexpected, nonreciprocal chiroptical activity in both absorption and emission, including a complete inversion of the chiroptical profile upon ...
Filippo Petri   +3 more
wiley   +1 more source

Localized Prostate Cancer Therapy: Tumor Microenvironment‐Activated Spermine Hydrogel With Real‐Time Autonomous Fluorescence Sensing

open access: yesChemistry – A European Journal, EarlyView.
First tumor microenvironment (TME)‐responsive spermine‐loaded hydrogel with autonomous sensing for advanced local therapy of prostate cancer (PCa) is developed. Spermine can be released from the hydrogel to kill the prostate cancer cells specifically under acidic TME.
Ho‐Fai Chau   +12 more
wiley   +1 more source

Defying Expectations: Extended Lifespan and Age-Related Telomere Dynamics in the Tropical Bat Species, <i>Molossus molossus</i>. [PDF]

open access: yesEcol Evol
Lonergan T   +9 more
europepmc   +1 more source

Community Head and Neck Cancer Knowledge, Engagement, Research, and Screening (CHECKERS): Protocol for a Community‐Engaged Approach to Head and Neck Cancer Prevention

open access: yesCancer Nexus, EarlyView.
ABSTRACT Introduction Unequal access to care is associated with disparities in prevention, early detection, and outcomes of head and neck cancer (HNC), especially in underserved populations. Community‐engaged research (CEnR) aims to build capacity for community members to address health inequity via bidirectional partnerships with healthcare ...
Nicholas A. Frisco   +11 more
wiley   +1 more source

An empirical Q-matrix validation method for the polytomous G-DINA model

open access: yes, 2019
Several empirically based Q-matrix validation methods are available in the literature. However, all the existing methods were developed for cognitive diagnosis models (CDMs) for dichotomous attributes.
Qiu, X   +3 more
core  

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke   +12 more
wiley   +1 more source

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