Results 101 to 110 of about 13,196,617 (310)
Structure and Function of Multimeric G-quadruplexes [PDF]
Molecules, 2019 G-quadruplexes are noncanonical nucleic acid structures formed from stacked guanine tetrads. They are frequently used as building blocks and functional elements in fields such as synthetic biology and also thought to play widespread biological roles.
Sofia Kolesnikova, Edward A. Curtis
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Molecular Therapy: Nucleic Acids, 2019 G-quadruplex structure forming motifs are among the most studied evolutionarily conserved drug targets that are present throughout the genome of different organisms and susceptible to influencing various biological processes.
Subodh Kumar Mishra +7 more
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Advanced Engineering Materials, EarlyView.A simplified thermoplastic pultrusion model is developed to predict thermal fields in glass fiber/polyethylene terephthalate (GF/PET) composites with reduced computational cost. By combining effective material homogenization, validation against literature data, and Gaussian‐process‐based optimization, the study reveals how heating limits, pulling speed,
Elder Soares +3 more
wiley +1 more source
G-Quadruplex DNA and RNA [PDF]
, 2019 G-quadruplexes (G4s) have become one of the most exciting nucleic acid secondary structures. A noncanonical, four-stranded structure formed in guanine-rich DNA and RNA sequences, G-quadruplexes can readily form under physiologically relevant conditions and are globularly folded structures.
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Feasibility of Nitrogen as a Carrier Gas for Inconel Cold Spray in Hydropower Application
Advanced Engineering Materials, EarlyView.N2, despite being nearly two orders of magnitude cheaper than He, is a feasible carrier gas for cold spray Inconel coatings in hydropower repair applications when higher gas temperature and pressure are used. Reducing powder size significantly improved cavitation resistance, while the addition of fine chromium carbide particles further enhanced erosion
Tianhao Wang +4 more
wiley +1 more source
Single-molecule visualisation of DNA G-quadruplex formation in live cells
Nature Chemistry, 2020 Substantial evidence now exists to support that formation of DNA G-quadruplexes (G4s) is coupled to altered gene expression. However, approaches that allow us to probe G4s in living cells without perturbing their folding dynamics are required to ...
M. Di Antonio +10 more
semanticscholar +1 more source
Advanced Engineering Materials, EarlyView.Grain boundary triple junctions are an essential ingredient of the microstructure of polycrystalline materials. In this study, a triple junction is observed using atomic‐resolution scanning transmission electron microscopy and characterized. Computer simulations reveal that the junction has a dislocation character that is determined by the joining ...
Tobias Brink +4 more
wiley +1 more source
Xanthene and Xanthone Derivatives as G-Quadruplex Stabilizing Ligands
Molecules, 2013 Following previous studies on anthraquinone and acridine-based G-quadruplex ligands, here we present a study of similar aromatic cores, with the specific aim of increasing G-quadruplex binding and selectivity with respect to duplex DNA.
Alessandro Altieri +7 more
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Advanced Engineering Materials, EarlyView.This work studies the anisotropic behavior of circular notched tensile specimens of Ni‐base superalloy single crystals during high‐temperature tensile creep along [001], [110], and [111]. Correlative scale‐bridging imaging of specimens reveals early rupture along [110] because 1) plastic deformation proceeds faster at notch center; 2) more (brittle ...
Leonardo Agudo Jácome +6 more
wiley +1 more source
Molbank, 2010 Cationic porphyrins interact strongly with guanine quadruplex DNA (G-quadruplex). We herein report the preparation of a cationic porphyrin bearing quinolinium side arms, 1,1’,1’’,1’’’-[porphyrin-5,10,15,20-tetrayltetrakis(3,1-phenylenemethylene)]tetra ...
Satoshi Fujii +3 more
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