Results 111 to 120 of about 11,711,774 (302)
Advanced Healthcare Materials, EarlyView.Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk +11 more
wiley +1 more source
G-quadruplex: A potential target for small molecules and proteins in anti-cancer drug investigation
Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ, 2018 DNA or RNA G-quadruplexes are secondary structures that occur in four-stranded Guanine-rich regions formed by stacked G-tetrads. The formation of DNA or RNA G-quadruplex structures plays a key role in many cellular biological processes such as DNA ...
Đặng Thanh Dũng +1 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.NeuroVisio SyncPatch integrates skin‐conformal electromyography (EMG) electrodes with camera‐tracked markers to jointly assess muscle activity and three‐dimensional knee kinematics during rehabilitation. Parallel feedback pathways provide real‐time kinematic guidance during movement and post‐trial neuromuscular feedback.
Bohyung Choi +11 more
wiley +1 more source
Molecules, 2019 G-quadruplexes have gained prominence over the past two decades for their role in gene regulation, control of anti-tumour activity and ageing. The physiological relevance and significance of these non-canonical structures in the context of cancer has ...
Pallavi Chilka +2 more
doaj +1 more source
DNA Damage Accelerates G‑Quadruplex Folding in a Duplex-G-Quadruplex-Duplex Context
Molecular details for the impact of DNA damage on folding of potential G-quadruplex sequences (PQSs) to noncanonical DNA structures involved in gene regulation are poorly understood.
Aaron M. Fleming (1314534) +3 more
core +1 more source
, 2019 The spectral properties of meso-tetrakis (N-methylpyridinium-4-yl)porphyrin (TMPyP) in the presence of parallel and antiparallel G-quadruplexes formed from a thrombin-binding aptamer G-quadruplex (5′-G3T2G3TGTG3T2G3) were investigated in this study.
Young-Ae Lee (177248) +5 more
core +1 more source
Can Elastomers Combine Stiffness, Toughness and Fatigue Resistance?
Advanced Materials, EarlyView.This review studies how the molecular and macroscopic architecture of elastomers influence their mechanical properties including: stiffness, stretchability, toughness, fatigue resistance, and damping behavior. By linking the structure to performance, it proposes design principles for advanced elastomeric systems that combine mechanical properties ...
Eva Baur, Esther Amstad
wiley +1 more source
Frontiers in Chemistry, 2014 Bis-indolinone derivatives having either 2,6-disubstituted pyridine core (1a and 1b) or 1,10-disubstituted phenanthroline core (2a and 2b), already known to have antitumor activity, have been tested as potential G-quadruplex binders.
Jussara eAmato +10 more
doaj +1 more source
Advanced Materials, EarlyView.Additively manufactured triply periodic minimal surface (TPMS) membranes offer an architecture‐driven alternative to hollow fiber bundles in artificial lungs. Multiphysics simulations and endothelialized prototypes show that the 3D‐printable membrane architecture improves gas exchange, blood flow distribution, and hemocompatibility, enabling ...
Michael Pflaum +14 more
wiley +1 more source