Aptamers Against the β-Conglutin Allergen: Insights into the Behavior of the Shortest Multimeric(Intra)Molecular DNA G-Quadruplex [PDF]
Ciara K. O’Sullivan +7 more
openalex +1 more source
This study examines how pore shape and manufacturing‐induced deviations affect the mechanical properties of 3D‐printed lattice materials with constant porosity. Combining µ‐CT analysis, FEM, and compression testing, the authors show that structural imperfections reduce stiffness and strength, while bulk material inhomogeneities probably enhance ...
Oliver Walker +5 more
wiley +1 more source
G-quadruplex: A potential target for small molecules and proteins in anti-cancer drug investigation
DNA or RNA G-quadruplexes are secondary structures that occur in four-stranded Guanine-rich regions formed by stacked G-tetrads. The formation of DNA or RNA G-quadruplex structures plays a key role in many cellular biological processes such as DNA ...
Đặng Thanh Dũng +1 more
doaj +1 more source
G-Quadruplexes Are Present in Human Coronaviruses Including SARS-CoV-2
The global coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is one of seven human coronaviruses. G-quadruplexes are intrinsic obstacles to genome replication.
Haoran Cui +3 more
doaj +1 more source
G4Hunter web application: a web server for G-quadruplex prediction
Motivation Expanding research highlights the importance of guanine quadruplex structures. Therefore, easy-accessible tools for quadruplex analyses in DNA and RNA molecules are important for the scientific community.
V. Brázda +6 more
semanticscholar +1 more source
Direct Evidence of Topological Dirac Fermions in a Low Carrier Density Correlated 5d Oxide
The 5d oxide BiRe2O6 is discovered as a low‐carrier‐density topological semimetal hosting symmetry‐protected Dirac fermions stabilized by nonsymmorphic symmetries. Angle‐resolved photoemission spectroscopy, quantum oscillations, and magnetotransport measurements reveal gapless Dirac cones, quasi‐2D Fermi surfaces, high carrier mobility, and a field ...
Premakumar Yanda +11 more
wiley +1 more source
Investigation on Quantitative Structure-Activity Relationships of 1,3,4 Oxadiazole Derivatives as Potential Telomerase Inhibitors [PDF]
The published manuscript is available at EurekaSelect via http://www.eurekaselect.com/164022/article, DOI : 10.2174/1570163815666180724113208. © 2018 Bentham ScienceA series of 1,3,4-oxadiazole derivatives with significant broad-spectrum anticancer ...
Almerico, Anna Maria +2 more
core +2 more sources
G-quadruplex forming sequences in the genome of all known human viruses: A comprehensive guide
G-quadruplexes are non-canonical nucleic acid structures that control transcription, replication, and recombination in organisms. G-quadruplexes are present in eukaryotes, prokaryotes, and viruses.
E. Lavezzo +7 more
semanticscholar +1 more source
Backbone Heterojunction Photocatalysts for Efficient Sacrificial Hydrogen Production
Herein, a ‘single‐component’ organic semiconductor photocatalyst is presented in which a molecular donor is bonded to a polymer acceptor. The resultant material demonstrates exceptional photocatalytic activity for hydrogen evolution in aqueous triethylamine with an outstanding external quantum efficiency of 38% at 420 nm.
Richard J. Lyons +11 more
wiley +1 more source
Targeting DNA G-quadruplexes with helical small molecules. [PDF]
We previously identified quinoline-based oligoamide helical foldamers and a trimeric macrocycle as selective ligands of DNA quadruplexes. Their helical structures might permit targeting of the backbone loops and grooves of G-quadruplexes instead of the G-
Balasubramanian, Shankar +9 more
core +3 more sources

