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Probing Residual Water in G-Quadruplex Structures through Molecular Vibrations. [PDF]

open access: yesJ Phys Chem B
Libera V   +10 more
europepmc   +1 more source

Impact of Thymidine Loop Modifications on Telomeric G-Quadruplex Catalytic Systems for Asymmetric Sulfoxidation. [PDF]

open access: yesMolecules
Finamore C   +8 more
europepmc   +1 more source
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Recent advances on G-quadruplex for biosensing, bioimaging and cancer therapy

TrAC - Trends in Analytical Chemistry, 2021
G-quadruplex is a three-dimensional secondary structure of nucleic acids formed by the Hoogsteen hydrogen pairing of four guanines. Diverse topologies of G-quadruplex could be employed in biosensing and bioimaging. By intercalating fluorescence dyes into
Jiaqi Xu, Hailun He, Changbei Ma
exaly   +2 more sources

RNA G-Quadruplexes: G-quadruplexes with ā€œUā€ Turns

Current Pharmaceutical Design, 2012
G-quadruplexes are non canonical secondary structures held together by Hoogsteen bonded planar guanine quartets formed in G-rich sequences in DNA and RNA. Considerable research over the past three decades has contributed to a great deal of understanding of these unusual structures in DNA.
Tani, Agarwal   +4 more
openaire   +2 more sources

Bulges in G-Quadruplexes: Broadening the Definition of G-Quadruplex-Forming Sequences

Journal of the American Chemical Society, 2013
We report on the first solution structure of an intramolecular G-quadruplex containing a single bulge and present evidence for extensive occurrence of bulges in different G-quadruplex contexts. The NMR solution structure of the d(TTGTGGTGGGTGGGTGGGT) sequence reveals a propeller-type parallel-stranded G-quadruplex containing three G-tetrad layers ...
Anh Tuan Phan
exaly   +3 more sources

G-quadruplex dynamics

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2017
G-quadruplexes (GQs) are four-stranded nucleic acid secondary structures formed by guanosine (G)-rich DNA and RNA sequences. It is becoming increasingly clear that cellular processes including gene expression and mRNA translation are regulated by GQs. GQ structures have been extensively characterized, however little attention to date has been paid to ...
Robert W, Harkness   +1 more
openaire   +2 more sources

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