Results 261 to 270 of about 32,953 (312)

When the Position of Pendant Groups Makes the Difference in G-Quadruplex Behavior: The Case of Bis-Conjugated Thrombin-Binding Aptamers. [PDF]

J Chem Inf Model
Platella C, Battistini F, Riccardi C, Smietana M, Morvan F, Orozco M, Montesarchio D.   +6 more
europepmc   +1 more source

AND‐Logic‐Gated Aptamer Switch for Precise Targeting and Regulation of RNA G‐Quadruplexes

Angewandte Chemie, EarlyView.
An AND‐logic‐gated aptamer switch enables tumor‐selective activation of RNA G‐quadruplex (rG4)‐targeting function. By combining cell‐surface recognition and intracellular redox sensing, the system achieves precise regulation of disease‐relevant RNA structures exclusively in tumor cells, with minimal off‐target effects in normal cells, offering a ...
Dan Wang, Ying Feng, Chun Kit Kwok
wiley   +1 more source

Deciphering the intermolecular interactions between G-quadruplex (G4)-forming sequences. [PDF]

Nucleic Acids Res
Xia J, Zhou J, Zhuang X, Ju H, Monchaud D, Chaires JB, Šponer J, Mergny JL, Zhou J.   +8 more
europepmc   +1 more source

Selective Nitrate Transmembrane Transport Through Adaptive Weak C─H Bonding Cyanostilbene Water Channels

Angewandte Chemie, EarlyView.
Here we demonstrate that weak HB CH donor cyanostilbenes promote water/ion transport through their ability to form less‐ordered transient water channels within the lipid bilayer with increased water permeability and NO3−/ Cl− selectivity. ABSTRACT Transmembrane water transport strongly depends on how dynamic, translocating water clusters are stabilized
Ioan Stroia, Dan‐Dan Su, Yuhao Li, Niculina Hadade, Ion Grosu, Arie van der Lee, Mihail Barboiu   +6 more
wiley   +1 more source

RPA hyperphosphorylation hinders the resolution of R-loops and G-quadruplex-associated R-loops during RAS-driven senescence. [PDF]

Nucleic Acids Res
Cortolezzis Y, Tolotto V, Triboli L, Picco R, Soler MA, Fortuna S, Bettin G, D'Este F, Carlassara E, Magris G, Miller KM, Angelini A, Xodo LE, Di Giorgio E.   +13 more
europepmc   +1 more source

A Label-Free G-Quadruplex/Thioflavin T Fluorescent Sensor for ClO^- Detection: Implications for Stress-Induced Hypertension Biomarker Analysis. [PDF]

Biosensors (Basel)
Liu J, Zhao Y, Zhang L, Liu H, Zhang G.
europepmc   +1 more source

Inhibition of DDX5-Mediated G-Quadruplex Unwinding in the β-Catenin 5'-UTR by Magnesium Isoglycyrrhizinate Alleviates Chemotherapy-Induced Intestinal Injury. [PDF]

Research (Wash D C)
Zhang Y, Fu W, Wang Y, Wu A, Zhu Z, Yin X, Li Y, Sun Y, Shi W, Cheng J, Hu L, Liu J, Cui J.   +12 more
europepmc   +1 more source

Light-Activated Molecules Targeting G-Quadruplex Nucleic Acids. [PDF]

Chemistry
Dudek M, Cabanetos C, Deiana M.
europepmc   +1 more source

L-RNA Aptamer-Based Tools for G-Quadruplex Structure: Identification, Characterization, and Application. [PDF]

Acc Chem Res
Ji D, Zhang K, Yarshova M, Kwok CK.
europepmc   +1 more source

NMR-based conformational analysis of DNA G-quadruplex guides mapping essential structure-function relationship in protein chaperoning.

Phys Chem Chem Phys
Negi D, Huang Z, Son A, Sathyamoorthy B, Horowitz S.   +4 more
europepmc   +1 more source