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Energetics of Ligand Binding to G-Quadruplexes

2012
G-quadruplex ligands are potential anticancer agents as telomerase inhibitors and potential transcriptional regulators of oncogenes. The search for best-in-class drugs is addressed to identify small molecules able to promote and stabilize G-quadruplex structures. What features should the G-quadruplex ligands possess?
GIANCOLA, CONCETTA, PAGANO, BRUNO
openaire   +3 more sources

Reversible Photoswitching of a G‐Quadruplex

Angewandte Chemie, 2009
Shinzi, Ogasawara, Mizuo, Maeda
openaire   +2 more sources

Recent advances on G-quadruplex for biosensing, bioimaging and cancer therapy

TrAC - Trends in Analytical Chemistry, 2021
Jiaqi Xu, Hailun He, Changbei
exaly  

Selective Interactions of Cationic Porphyrins with G-Quadruplex Structures

Journal of the American Chemical Society, 2001
Haiyong Han   +2 more
exaly  

A Model of Smart G-Quadruplex Ligand

Journal of the American Chemical Society, 2013
Romain Haudecoeur   +2 more
exaly  

G-Quadruplex: A Regulator of Gene Expression and Its Chemical Targeting

CheM, 2018
Tian Tian, Shao-Ru Wang, Xiang Zhou
exaly  

Structure of the Human Telomere in K + Solution:  An Intramolecular (3 + 1) G-Quadruplex Scaffold

Journal of the American Chemical Society, 2006
Anh Tuan Phan, Laurent Lacroix
exaly  

Design and Synthesis of an Expanded Porphyrin That Has Selectivity for the c-MYC G-Quadruplex Structure

Journal of the American Chemical Society, 2005
Hariprasad Vankayalapati   +2 more
exaly  

Telomestatin and Diseleno Sapphyrin Bind Selectively to Two Different Forms of the Human Telomeric G-Quadruplex Structure

Journal of the American Chemical Society, 2005
W David Wilson, Laurence H Hurley
exaly  

Highly Efficient G-Quadruplex Recognition by Bisquinolinium Compounds

Journal of the American Chemical Society, 2007
Jean-Louis Mergny   +2 more
exaly  

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