Results 191 to 200 of about 1,376,328 (285)

Physicians' opinions on barriers to patient counseling on physical activity in primary care: focus on physicians' healthy exercise habits and knowledge about physical activity. [PDF]

Front Med (Lausanne)
Fominiene VB, Fominaite M, Sipaviciene S.   +2 more
europepmc   +1 more source

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

Advanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang, Bin Li, Zhijin Fan, Yan Yan, Fei Ma, Changting He, Shiping Liu, Mingliang Pan, Zhou Pan, Huijuan Wang, Xinting Fu, Jiamei Wang, Yue Jia, Qin Gu, Duo Jiang, Xueting Liu, Bohua Ren, Qinqin Wang, Yuehua Hei, Han Duan, Yanqiu Wu, Zihui Wei, Liying Zhan, Yuhui Liao   +23 more
wiley   +1 more source

Evaluating the effectiveness of preventive training programs in reducing the incidence of knee injuries: a systematic review and meta-analysis. [PDF]

Front Public Health
Zhou H, Xing YM, Zhou DL, Cui L, Qian J, Li JN, Bu YF.   +6 more
europepmc   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

Advanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi, Jingrui Cao, Tong Wu, Guang Yang, YaWen Yang, Shixin Zhang, Wenwen Su, Hongyu Chu, Yangyang Zhao, Shan Jiang, Qiong Wu, Dongxu Jiao, Fangfang Chen   +12 more
wiley   +1 more source

A model-based prion vaccine protects a transgenic mouse line carrying a Gerstmann-Sträussler-Scheinker disease mutation. [PDF]

Acta Neuropathol
Fang A, Tang X, Fleming M, Tancowny B, Wang X, Wang Y, Daude N, Dorosh L, Fleck SC, Rathod V, Coustou V, Cervantes SA, Velásquez CD, Westaway D, Aiken J, McKenzie D, Telling G, Stepanova M, Saupe SJ, Siemer AB, Wille H.   +20 more
europepmc   +1 more source

Netrin-G1 [PDF]

, 2020
openaire   +1 more source

Cells Dynamically Adapt Their Nuclear Volumes and Proliferation Rates During Single to Multicellular Transitions

Advanced Science, EarlyView.
It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan, Keshav Gajendra Babu, Markus Mukenhirn, Antje Garside, Vinita Ajit Kini, Trishla Adhikari, Timon Beck, Byung Ho Lee, Kyoohyun Kim, Carsten Werner, Raimund Schlüßler, Alf Honigmann, Sebastian Aland, Anna Verena Taubenberger   +13 more
wiley   +1 more source

Arbitrary Orthogonal Polarization Decomposition and Routing With Complex Amplitude Modulation via Wheel‐of‐Fortune‐Inspired Metasurfaces

Advanced Science, EarlyView.
This work demonstrates a receiver‐transmitter‐integrated metasurface that decomposes an incident wave into orthogonal components and routes them into separate channels. Inspired by a “Wheel‐of‐Fortune” mechanism, it enables independent control over the amplitude, phase, and polarization of the transmitted wave.
Tong Liu, Changhong Dai, Weike Feng, Yanzhao Wang, Wenxin Liu, Wentao Zhang, Chao Tian, Guangwei Hu, He‐Xiu Xu   +8 more
wiley   +1 more source

Genomic Insights into Local Adaptation and Evolutionary Trajectories of <i>Propylea japonica</i>. [PDF]

Biomolecules
Zhang L, Shi Y, Wang M, Xu Y, Yang X, Zhao M, Li W, Guo X, Zhao C, Xi Y.   +9 more
europepmc   +1 more source

G1-Phase [PDF]

, 2019
openaire   +1 more source