Results 21 to 30 of about 12,487 (187)

Order imbalance and commonality: Evidence from the options market

open access: yesBorsa Istanbul Review, 2022
Using a market model and principal component analysis, we investigate the existence of common effects in order imbalance in the Borsa Istanbul's option market.
John Omole, Ahmet Sensoy, Guzhan Gulay
doaj   +1 more source

Insights into divalent cation regulation and G13-coupling of orphan receptor GPR35

open access: yesCell Discovery, 2022
Endogenous ions play important roles in the function and pharmacology of G protein-coupled receptors (GPCRs) with limited atomic evidence. In addition, compared with G protein subtypes Gs, Gi/o, and Gq/11, insufficient structural evidence is accessible ...
Jia Duan   +12 more
doaj   +1 more source

Discovery of potent tubulin inhibitors targeting the colchicine binding site via structure-based lead optimization and antitumor evaluation

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2023
The colchicine binding site of tubulin is a promising target for discovering novel antitumour agents. Previously, we identified 2-aryl-4-amide-quinoline derivatives displayed moderate tubulin polymerisation inhibitory activity and broad-spectrum in vitro
Wei Liu   +8 more
doaj   +1 more source

Conformational Activation of Radixin by G13 Protein α Subunit [PDF]

open access: yesJournal of Biological Chemistry, 2000
G(13) protein, one of the heterotrimeric guanine nucleotide-binding proteins (G proteins), regulates diverse and complex cellular responses by transducing signals from the cell surface presumably involving more than one pathway. Yeast two-hybrid screening of a mouse brain cDNA library identified radixin, a member of the ERM family of three closely ...
R, Vaiskunaite   +5 more
openaire   +2 more sources

G13(P) Are Educational Supervisors Ready For START? [PDF]

open access: yesArchives of Disease in Childhood, 2013
Aims START is a new compulsory assessment for final year trainees introduced by the RCPCH in 2012. The purpose of START is to provide targeted developmental feedback, a process which is critically dependent on engagement and understanding from trainees and educational supervisors.
S. Minson, A. Brightwell
openaire   +1 more source

TSH Activates Macrophage Inflammation by G13- and G15-dependent Pathways

open access: yesEndocrinology, 2021
AbstractThyroid-stimulating hormone (TSH) treatment activates inhibitor of NF-κB/nuclear factor κB (IκB/NFκB) and extracellular signal-regulated kinase (ERK)–P38 in macrophages, but how these pathways are activated, and how they contribute to the proinflammatory effect of TSH on macrophages remain unknown.
Chongbo Yang   +6 more
openaire   +2 more sources

An Assessment of Wind Farm Construction Efficiency Using the Real Option Method

open access: yesFolia Oeconomica Stetinensia, 2016
From a developer’s point of view the construction of a wind farm in Poland is an investment project assessed in terms of economic efficiency. This paper discusses the selection of methods to be used for the assessment of such investments: it proposes to ...
Łukaszewski Tomasz, Głoćko Wojciech
doaj   +1 more source

Pricing options with dual volatility input to modular neural networks

open access: yesBorsa Istanbul Review, 2020
Tested is the choice of the volatility input to the artificial neural networks in the process of pricing options. Numerous studies concluded the weaknesses of Black-Scholes model use as a pricing tool in the market.
Sadi Fadda
doaj   +1 more source

AMMI analysis of genotype × environment interaction on grain yield of sesame (Sesamum indicum L.) genotypes in Iran

open access: yesBiotechnology & Biotechnological Equipment, 2020
In this study, we investigated the effect of genotype × environment interaction (GEI) on the grain yield of 15 different sesame genotypes on four test areas (Arak, Birjand, Karaj and Shiraz) in two years (2017–2018).
Hossein Movahedi   +3 more
doaj   +1 more source

Optimal hedge ratios and hedging effectiveness: An analysis of the Turkish futures market

open access: yesBorsa Istanbul Review, 2022
The main purpose of this comprehensive study is to determine the optimal hedge ratios and hedging effectiveness of different futures contracts traded on the Borsa Istanbul (BIST), namely the BIST 30 equity index, US dollar–Turkish lira currency futures ...
Goknur Buyukkara   +2 more
doaj   +1 more source

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