Results 51 to 60 of about 14,047 (215)
Business Strategy and the Environment, EarlyView.ABSTRACT This study systematizes the literature on eco‐innovation and economic complexity, aiming to understand how the sophistication of productive structures shapes countries' capacity to develop environmentally responsible innovations, and how eco‐innovation may, in turn, influence productive sophistication.
Gregory Matheus Pereira de Moraes +1 more
wiley +1 more source
Antagonistic Regulation of Neurite Morphology through Gq/G11 and G12/G13 [PDF]
Journal of Biological Chemistry, 2008 The induction of neurite retraction and growth cone collapse via G-protein-coupled receptors is involved in developmental as well as regenerative processes. The role of individual G-protein-mediated signaling processes in the regulation of neurite morphology is still incompletely understood. Using primary neurons from brains lacking Galpha(q)/Galpha(11)
Alexander, Nürnberg +3 more
openaire +2 more sources
Drug Testing and Analysis, EarlyView.A fatal 3‐chloro‐phencyclidine (3‐Cl‐PCP) intoxication was investigated by analyzing postmortem samples and a pooled human liver microsomes assay. Tentative metabolite identification was performed by liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐QTOF‐MS). Seven phase I metabolites were identified.
Johannes Kutzler +3 more
wiley +1 more source
Overlap in signaling between Smoothened and the α subunit of the heterotrimeric G protein G13. [PDF]
PLoS ONE, 2018 The Hedgehog family of morphogens has long been known to utilize, through the 7-transmembrane protein Smoothened (Smo), the heterotrimeric G protein Gi in both canonical and noncanonical forms of signaling.
Xueshui Guo +4 more
doaj +1 more source
Regions on Adenylyl Cyclase VII Required for Selective Regulation by the G13 Pathway [PDF]
Molecular Pharmacology, 2013 Regulation of multiple adenylyl cyclases (AC) provides unique inputs to mediate the synthesis of cAMP, a ubiquitous second messenger that controls many aspects of cellular function. On stimulation by G(s), the activities of ACs can be further selectively modulated by other pathways to ensure precise control of intracellular cAMP responses to specific ...
Lily I, Jiang +2 more
openaire +2 more sources
An SSI‐Informed Design for Tuned Mass Dampers With Small‐to‐Large Mass Ratios
Earthquake Engineering &Structural Dynamics, EarlyView.ABSTRACT Tuned Mass Dampers (TMDs) are used to mitigate structural vibrations induced by seismic or wind excitation, by tuning the device to the system's dominant resonant frequencies. However, the TMD effectiveness can be undermined by soil‐structure interaction, which can lead to elongation of the vibration periods and to combined translational ...
Davide Noè Gorini +3 more
wiley +1 more source
Sequence‐Encoded Frustration Directs the Formation of Abridged G‐Quadruplex Architectures
Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.Programmable frustration reshapes the free‐energy surface (FES) of guanine‐quadruplex (G4) folding, stabilizing an abridged G4 and a G‐triplex intermediate. ABSTRACT Frustration—competing interactions that cannot be simultaneously optimized—shapes energy landscapes in proteins and soft matter, but has rarely been exploited as a programmable design ...
Yuncheng Qian +6 more
wiley +2 more sources
The Molecular Heterogeneity of NRAS Variants in Thyroid Nodules
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective NRAS variants are the most common mutations in thyroid nodules with (B)ethesda III/IV cytology. This study aims to characterize co‐occurring variants, molecular signatures, and hallmarks of cancer pathways in nodules with NRAS variants. Study Design Retrospective database analysis.
Emma De Ravin +5 more
wiley +1 more source
Determination of poly-B-hydroxybutyrate (PHB) production in different media by Pseudomonas cepacia G13 strain [PDF]
, 2005 In this study, Poly-beta-hydroxybutyrate (PHB) accumulation was investigated in Pseudomonas cepacia G13 strain. Determination of the amount of PHB was performed chemically.
ASLIM, Belma +5 more
core
Anaphylactic shock depends on endothelial Gq/G11 [PDF]
, 2009 Anaphylactic shock is a severe allergic reaction involving multiple organs including the bronchial and cardiovascular system. Most anaphylactic mediators, like platelet-activating factor (PAF), histamine, and others, act through G protein – coupled ...
Nina Wettschureck +29 more
core +1 more source