Results 51 to 60 of about 15,247 (207)

Simulating stock prices using geometric Brownian motion model under normal and convoluted distributional assumptions

Scientific African, 2023
This study proposes a modified Geometric Brownian motion (GBM), to simulate stock price paths under normal and convoluted distributional assumptions. This study utilised four selected continuous probability distributions for the convolution because of ...
Eric Teye Mensah, Alexander Boateng, Nana Kena Frempong, Daniel Maposa   +3 more
doaj   +1 more source

Evaluating Testability of Permafrost Models Through Physical and Thermal Testing in Complex Mountain Terrain, Yukon, Canada

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT Due to its subsurface nature, permafrost cannot be directly observed with the naked eye or optical remote sensing. Consequently, accurately describing its distribution and thermal state is challenging. This is especially true in vast, remote environments, where obtaining comprehensive field data is demanding or improbable.
Ria Nicholson, Philip P. Bonnaventure, Nick C. Noad, Madeleine C. Garibaldi, Rabecca Thiessen, Will Kochtitzky   +5 more
wiley   +1 more source

Option pricing with neural networks vs. Black-Scholes under different volatility forecasting approaches for BIST 30 index options

Borsa Istanbul Review, 2022
This study compares the performances of neural network and Black-Scholes models in pricing BIST30 (Borsa Istanbul) index call and put options with different volatility forecasting approaches.
Zeynep İltüzer
doaj   +1 more source

Integrative Modeling in the Age of Machine Learning: A Summary of HADDOCK Strategies in CAPRI Rounds 47–55

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The HADDOCK team participated in CAPRI rounds 47–55 as server, manual predictor, and scorers. Throughout these CAPRI rounds, we used a plethora of computational strategies to predict the structure of protein complexes. Of the 10 targets comprising 24 interfaces, we achieved acceptable or better models for 3 targets in the human category and 1 ...
Victor Reys, Marco Giulini, Vlad Cojocaru, Anna Engel, Xiaotong Xu, Jorge Roel‐Touris, Cunliang Geng, Francesco Ambrosetti, Brian Jiménez‐García, Zuzana Jandova, Panagiotis I. Koukos, Charlotte van Noort, João M. C. Teixeira, Siri C. van Keulen, Manon Réau, Rodrigo V. Honorato, Alexandre M. J. J. Bonvin   +16 more
wiley   +1 more source

Antagonistic Regulation of Neurite Morphology through Gq/G11 and G12/G13 [PDF]

Journal of Biological Chemistry, 2008
The induction of neurite retraction and growth cone collapse via G-protein-coupled receptors is involved in developmental as well as regenerative processes. The role of individual G-protein-mediated signaling processes in the regulation of neurite morphology is still incompletely understood. Using primary neurons from brains lacking Galpha(q)/Galpha(11)
Alexander, Nürnberg, Anja U, Braüer, Nina, Wettschureck, Stefan, Offermanns   +3 more
openaire   +2 more sources

Side‐by‐side long‐term performance assessment of GFRP‐ and steel‐reinforced concrete bridge decks

Structural Concrete, EarlyView.
Abstract The corrosion‐induced deterioration of steel‐reinforced bridge decks is a service life concern, especially in cold regions, where the use of deicing chemicals is common. To address this issue, glass fiber‐reinforced polymer (GFRP) reinforcement has received growing attention, owing to the GFRP's resistance to conventional corrosion.
Shadi Azad, Dikshant Saini, Behrouz Shafei   +2 more
wiley   +1 more source

Overlap in signaling between Smoothened and the α subunit of the heterotrimeric G protein G13. [PDF]

PLoS ONE, 2018
The Hedgehog family of morphogens has long been known to utilize, through the 7-transmembrane protein Smoothened (Smo), the heterotrimeric G protein Gi in both canonical and noncanonical forms of signaling.
Xueshui Guo, Natalia A Riobo-Del Galdo, Eun Ji Kim, Gregory R Grant, David R Manning   +4 more
doaj   +1 more source

Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13 [PDF]

Journal of Biochemistry, 2011
G protein-mediated signal transduction can transduce signals from a large variety of extracellular stimuli into cells and is the most widely used mechanism for cell communication at the membrane. The RhoGTPase family has been well established as key regulators of cell growth, differentiation and cell shape changes.
Tohru, Kozasa, Nicole, Hajicek, Christina R, Chow, Nobuchika, Suzuki   +3 more
openaire   +2 more sources

Capturing Children's Voices in Healthcare: Development of the PREM‐Ped Questionnaire

Acta Paediatrica, EarlyView.
ABSTRACT Aim Patient‐reported experience measures (PREMs) capture how care is experienced and are essential quality indicators in paediatric healthcare, supporting children's right to be heard. Compared with patient‐reported outcome measures (PROMs), which assess health status and well‐being, PREMs are less developed, particularly for children.
E. Broström, J. Granhagen Jungner, C. Bartholdson, S. Norgren, M. Wenemark   +4 more
wiley   +1 more source

Systematic profiling reveals broad G protein coupling and context‐dependent modulation of cyclic AMP by the orphan receptor GPR139

British Journal of Pharmacology, EarlyView.
Background and Purpose G protein‐coupled receptors (GPCRs) are major drug targets, yet many orphan receptors remain poorly characterized. GPR139 has been implicated in CNS disorders, including schizophrenia and depression, but its signalling mechanisms remain unclear.
Boris Trapkov, Hans Bräuner, Alexander Sebastian Hauser   +2 more
wiley   +1 more source