Dissecting the Chemical and Thermal Stabilities of Tetrads in G-Quadruplexes to Derive a Structure-Activity Relation for a Thrombin-Binding DNA G-Quadruplex Aptamer. [PDF]
Extended variants of the G‐quadruplex thrombin binding aptamer exhibit differential anticoagulation activities. We show that 3’ terminal extensions increase nuclease resistance, while variations in thermal stability directly impact activity. Hydrogen exchange nuclear magnetic resonance spectroscopy (NMR) report on thermodynamic properties of the base ...
Wirmer-Bartoschek J +3 more
europepmc +2 more sources
How to fly to safety without overpaying for the ticket
For most active investors treasury bonds (govs) provide diversification and thus reduce the risk of a portfolio. These features of govs become particularly desirable in times of elevated risk which materialize in the form of the flight-to-safety (FTS ...
Kaczmarek Tomasz, Grobelny Przemysław
doaj +1 more source
The choice of external financing source: The role of company size and stock liquidity
This paper aims to answer whether firms of different sizes and stock liquidities differ in the choice of external sources of financing in companies listed in CEE countries. To this end the net debt issuance is regressed on the financial deficit.
Stereńczak Szymon, Kubiak Jarosław
doaj +1 more source
Soil Disturbing Agent-Creation and Application of “G15” Series Products
Diseases caused by two or more soil-borne pathogens are called compound soil-borne diseases. We have pioneered the "root splitter" and the imaging analysis system, providing a new tool for studying compound soil-borne diseases and a new method for evaluating crop resistance and pesticide (fertilizer) efficacy, and laying a foundation for the ...
Jun Liu +4 more
openaire +1 more source
The Circumgalactic Medium of Submillimeter Galaxies. II. Unobscured QSOs within Dusty Starbursts and QSO Sightlines with Impact Parameters below 100 Kiloparsec [PDF]
We present Atacama Large Millimeter/submillimeter Array (ALMA) 870um observations of 29 bright Herschel sources near high-redshift QSOs. The observations confirm that 20 of the Herschel sources are submillimeter-bright galaxies (SMGs) and identify 16 new
Casey, Caitlin M. +6 more
core +2 more sources
Blood ties: ABO is a trans-species polymorphism in primates [PDF]
The ABO histo-blood group, the critical determinant of transfusion incompatibility, was the first genetic polymorphism discovered in humans. Remarkably, ABO antigens are also polymorphic in many other primates, with the same two amino acid changes ...
A. Venkat +38 more
core +3 more sources
نقش مناسبتهای تاریخی اسلامی در ارتباط بین گرایشهای احساسی سرمایهگذاران و بازده سهام با تأکید بر متغیّر تعدیلگر حاکمیت شرکتی [PDF]
هدف این پژوهش، بررسی نقش مناسبتهای تاریخی اسلامی بر رابطه بین گرایشهای احساسی سرمایهگذاران و بازدهسهام با تأکید برمتغیّر تعدیلگر حاکمیت شرکتی است. منظور از مناسبتهای تاریخی اسلامی، ماههای رمضان و محرم هستند.
عبدالغفور محمدزاده +2 more
doaj +1 more source
Laboratory Tests Of Waste Mixtures Consisting Recycled Tyre Rubber and Coal-Mining Wastes [PDF]
The paper presents the results of research on the application of recycled tyre rubber, in the form of rubber dust, in mixtures bound with a hydraulic binder, to improve the physical and mechanical parameters of unburnt coalmining slates.
Ciolczyk, Adrian, Walotek, Konrad
core +1 more source
Credit rating announcement and bond liquidity: the case of emerging bond markets [PDF]
Purpose – This study examines the effect of the informational content of local credit rating announcements in emerging markets on the liquidity of their bond markets.
Amir Saadaoui +2 more
doaj +1 more source
The transmission mechanism has been dominated by direct monetary measures since the crisis of 2008. While the indirect impacts of the unconventional monetary instruments have not been fully explored yet.
Mészáros Mercédesz +1 more
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