Results 11 to 20 of about 7,092,513 (195)

CARM1 S217 phosphorylation by CDK1 in late G2 phase facilitates mitotic entry [PDF]

open access: yesCell Death and Disease
The coactivator-associated arginine methyltransferase 1 (CARM1) functions as an epigenetic writer, however, its role in mitosis remains poorly understood.
Yena Cho   +3 more
doaj   +2 more sources

DNA damage during G2 phase does not affect cell cycle progression of the green alga Scenedesmus quadricauda. [PDF]

open access: yesPLoS ONE, 2011
DNA damage is a threat to genomic integrity in all living organisms. Plants and green algae are particularly susceptible to DNA damage especially that caused by UV light, due to their light dependency for photosynthesis.
Monika Hlavová   +4 more
doaj   +2 more sources

TLC388 Induces DNA Damage and G2 Phase Cell Cycle Arrest in Human Non-Small Cell Lung Cancer Cells [PDF]

open access: yesCancer Control, 2020
TLC388, a camptothecin-derivative targeting topoisomerase I, is a potential anticancer drug. In this study, its effect on A549 and H838 human non-small cell lung cancer (NSCLC) cells was investigated.
Kun-Ming Wu MD   +4 more
doaj   +2 more sources

Mechanism for G2 phase-specific nuclear export of the kinetochore protein CENP-F. [PDF]

open access: yesCell Cycle, 2017
Loftus KM   +6 more
europepmc   +2 more sources

MYB3R-SCL28-SMR module with a role in cell size control negatively regulates G2 progression in Arabidopsis

open access: yesPlant Signaling & Behavior, 2023
Cell size control is one of the prerequisites for plant growth and development. Recently, a GRAS family transcription factor, SCARECROW-LIKE28 (SCL28), was identified as a critical regulator for both mitotic and postmitotic cell-size control.
Hirotomo Takatsuka   +9 more
doaj   +1 more source

Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1

open access: yesLife Science Alliance, 2021
Main mitotic kinases as PLK1 are activated at the S/G2 transition. A change in Cyclin A2 localisation at the S/G2 transition enables activation of PLK1. Cyclin A2 is a key regulator of the cell cycle, implicated both in DNA replication and mitotic entry.
Helena Silva Cascales   +8 more
doaj   +1 more source

Visualizing Vpr-induced G2 arrest and apoptosis. [PDF]

open access: yesPLoS ONE, 2014
Vpr is an accessory protein of human immunodeficiency virus type 1 (HIV-1) with multiple functions. The induction of G2 arrest by Vpr plays a particularly important role in efficient viral replication because the transcriptional activity of the HIV-1 ...
Tomoyuki Murakami, Yoko Aida
doaj   +1 more source

Ras‐dependent cell cycle commitment during G2 phase [PDF]

open access: yesFEBS Letters, 2001
Synchronization used to study cell cycle progression may change the characteristics of rapidly proliferating cells. By combining time‐lapse, quantitative fluorescent microscopy and microinjection, we have established a method to analyze the cell cycle progression of individual cells without synchronization.
Hitomi, Masahiro, Stacey, Dennis W.
openaire   +2 more sources

AMPK Activity Contributes to G2 Arrest and DNA Damage Decrease via p53/p21 Pathways in Oxidatively Damaged Mouse Zygotes

open access: yesFrontiers in Cell and Developmental Biology, 2020
In zygotes, the capacity of G2/M checkpoint and DNA repair mechanisms to respond to DNA damage varies depending on different external stressors. In our previous studies, we found that mild oxidative stress induced a G2/M phase delay in mouse zygotes ...
Pei He   +10 more
doaj   +1 more source

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