Plasmodium falciparum clearance with artemisinin-based combination therapy (ACT) in patients with glucose-6-phosphate dehydrogenase deficiency in Mali [PDF]
, 2010 URL : http://www.malariajournal.com/content/9/1/332Background: Artemisinin-based combination therapy (ACT) is currently the most effective medicine for the treatment of uncomplicated malaria.
Abdoulaye K Kone +9 more
core +2 more sources
Advances in Human Biology, 2019 Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most significant enzyme defect in India with an incidence ranging from 2% to 27.9% in different communities.
Seema Sharma, Milap Sharma
doaj +1 more source
Prospective evaluation of BDProbeTec strand displacement amplification (SDA) system for diagnosis of tuberculosis in non-respiratory and respiratory samples. [PDF]
, 2004 Nucleic acid amplification techniques (NAATs) have been demonstrated to make significant improvements in the diagnosis of tuberculosis (TB), particularly in the time to diagnosis and the diagnosis of smear-negative TB. The BD ProbeTec strand displacement
Billington, OJ +7 more
core +2 more sources
Impact of the method of G6PD deficiency assessment on genetic association studies of malaria susceptibility. [PDF]
PLoS ONE, 2009 BACKGROUND:Clinical association studies have yielded varied results regarding the impact of glucose-6-phosphate dehydrogenase (G6PD) deficiency upon susceptibility to malaria.
Marla K Johnson +4 more
doaj +1 more source
Qatar Medical Journal, 2004 G6PD deficiency is the most common enzyme deficiency disease worldwide, affecting 10% of the world's population. It is an X linked recessive disease therefore it affects males more than females (females are usually carriers of the disease).
A. Al Muzrakchi, A. A. Gehani
openaire +1 more source
Heliyon, 2023 Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a genetic disorder caused by a structural abnormality in the enzyme. G6PD deficiency is most prevalent among African, Asian, and Mediterranean people.
Woldeteklehaymanot Kassahun +3 more
doaj +1 more source
G6PD deficiency does not enhance susceptibility for acquiring Helicobacter pylori infection in Sardinian patients [PDF]
, 2016 Background: Subjects with glucose-6-phosphate dehydrogenase (G6PD) deficiency may be more susceptible to infections due to impaired leukocyte bactericidal activity. The disorder is common in the Mediterranean area.
Dore, Maria Pina +4 more
core +2 more sources
Human G6PD variant structural studies: Elucidating the molecular basis of human G6PD deficiency [PDF]
, 2022 Glucose-6-phosphate dehydrogenase deficiency is by far the most prevalent human enzymopathy and is gener ated by a series of point mutations in the X-linked gene encoding G6PD.
Ab Latif, Nurriza +7 more
core +1 more source
Risk of pneumococcal bacteremia in Kenyan children with glucose-6-phosphate dehydrogenase deficiency
BMC Medicine, 2020 Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme deficiency state in humans. The clinical phenotype is variable and includes asymptomatic individuals, episodic hemolysis induced by oxidative stress, and chronic ...
James J. Gilchrist +10 more
doaj +1 more source
BMC Pediatrics, 2022 Background Screening for G6PD deficiency in newborns can help prevent severe hemolysis, hyperbilirubinemia, and bilirubin encephalopathy, as recommended by the World Health Organization (WHO).
Thanaporn Pimpakan +9 more
doaj +1 more source