Results 111 to 120 of about 7,778 (203)

Nine Different Glucose-6-phosphate Dehydrogenase (G6PD) Variants in a Malaysian Population with Malay, Chinese, Indian and Orang Asli (Aboriginal Malaysian) Backgrounds [PDF]

, 2008
The Malaysian people consist of several ethnic groups including the Malay, the Chinese, the Indian and the Orang Asli (aboriginal Malaysians). We collected blood samples from outpatients of 2 hospitals in the State of Selangor and identified 27 glucose-6-
Abdul Manand, Encik Abdul Salim, Arai, Meiji, Hidayah, Noor Ishak, Hirai, Makoto, Isa, Zaleha Mohamed, Luo, Enjie, Matsuoka, Hiroyuki, Wang, Jichun   +7 more
core   +1 more source

Malaria in Bangladesh, 2000–2025: Navigating the Headwinds From Control to Elimination

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Bangladesh has dramatically reduced its malaria burden since 2000, confining the disease to specific geographic zones. However, the national 2030 elimination goal is now threatened by a complex interplay of biological, ecological, and social factors.
Abdullaha Al Mamun, Mustafa Sarwar A. Kayenat, K. A. M. Inzamul Islam   +2 more
wiley   +1 more source

Long‐Term Follow‐Up of Patients With Transaldolase Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Transaldolase (TALDO) deficiency has a well‐characterized phenotype. However, there are few large cohort studies, and little is known about the long term, including the need for organ transplantation. Our aim was to share a long multicenter experience in managing these patients.
M. Scaglione, A. Brassier, A. Wiedemann, I. Jankowska, J. Pawłowska, T. Lamireau, L. Bridoux‐Henno, C. Douillard, T. Casswall, U. Cucinotta, M. Gaschignard, P. Socha, F. Feillet, B. Fischler, D. Samara‐Boustani, M. C. Schiaffino, M. Schiff, P. De Lonlay, F. Lacaille   +18 more
wiley   +1 more source

A novel point mutation in a class IV glucose-6-phosphate dehydrogenase variant (G6PD São Paulo) and polymorphic G6PD variants in São Paulo State, Brazil [PDF]

, 2009
In this study, we used red cell glucose-6-phosphate dehydrogenase (G6PD) activity to screen for G6PD-deficient individuals in 373 unrelated asymptomatic adult men who were working with insecticides (organophosphorus and carbamate) in dengue prevention ...
OLIVEIRA, Raimundo Antonio G., OSHIRO, Marilena, HIRATA, Mario H., HIRATA, Rosario D.C., RIBEIRO, Georgina S., MEDEIROS, Tereza M.D., BARRETTO, Orlando C. de O.   +6 more
core   +2 more sources

LKB1–AMPK Signaling Pathway in Cardiovascular and Other Diseases

MedComm, Volume 7, Issue 3, March 2026.
The LKB1–AMPK pathway has a central regulatory role in various diseases. Dysfunction of this pathway can lead to pathological processes in cardiovascular diseases (atrial fibrillation, myocardial infarction, myocardial hypertrophy, atherosclerosis), metabolic diseases (diabetes and kidney disease), neurodegenerative diseases (Alzheimer's disease ...
Zhuo Chen, Qin Yang, Guo‐Wei He
wiley   +1 more source

G6PD Deficiency in the Gulf Region: A Systematic Review of Prevalence, Genotypic, and Phenotypic Variants

Majmaah Journal of Health Sciences
IGlucose-6-phosphate dehydrogenase (G6PD) deficiency, an X-linked recessive disorder affecting approximately 400 million individuals globally, impairs red blood cells’ ability to counter oxidative stress, presenting primarily as neonatal jaundice and hemolytic anemia, with significant prevalence in malaria-endemic regions.
Yazeed Alekrish, Atheer Aljohani, Ghaidaa Almuhammadi, Mohammed Albalawi   +3 more
openaire   +1 more source

Unraveling A‐β+ ketosis‐prone diabetes: An evolving diagnosis with an elusive pathogenesis

Journal of Diabetes Investigation, Volume 17, Issue 3, Page 381-391, March 2026.
ABSTRACT Since the discovery of insulin over a century ago, how we conceptualize, describe and treat diabetes has evolved, paving the way for the identification of distinct diabetes subgroups and individualized treatment options. Historically, the term ketosis‐prone diabetes (KPD) has comprised a group of diabetes syndromes characterized by severe ...
Nina Suda, Gabrielle Page‐Wilson, Jacqueline Lonier, Utpal B. Pajvani   +3 more
wiley   +1 more source

Characterization of G6PD genotypes and phenotypes on the northwestern

, 2016
Mutations in the glucose-6-phosphate dehydrogenase (G6PD) gene result in red blood cells with increased susceptibility to oxidative damage. Significant haemolysis can be caused by primaquine and other 8-aminoquinoline antimalarials used for the radical treatment of Plasmodium vivax malaria.
Bancone, G, Chu, C, Somsakchaicharoen, R, Chowwiwat, N, Parker, D, Charunwatthana, P, White, N, Nosten, F   +7 more
openaire   +1 more source

A multicentre comparison of a novel surrogate marker for determining the specific potency of anti-tuberculosis drugs.

, 2003
A model for evaluating the potency of a new anti-tuberculosis drug or a drug combination, based on a decline in the number of viable tubercle bacilli in patient's sputum during 5 days mono-therapy has been reported.
Gillespie, Stephen H, Gosling, Roly D, Heifets, Leonid   +2 more
core   +1 more source

Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria [PDF]

, 2008
Besides existing artemisinin-based combination therapies, alternative safe, effective and affordable drug combinations against falciparum malaria are needed. Methylene blue (MB) was the first synthetic antimalarial drug ever used, and recent studies have
Coulibaly, Boubacar, Klose, Christina, Kouyaté, Bocar, Mansmann, Ulrich, Meissner, Peter E., Mockenhaupt, Frank P., Müller, Olaf, Schirmer, R. Heiner, Sié, Ali, Walter-Sack, Ingeborg, Zoungrana, Augustin   +10 more
core   +1 more source