Results 61 to 70 of about 7,778 (203)
Malaria Journal, 2019 Background Malaria transmission-blocking anti-malarial drugs, such as primaquine, offers an effective strategy for reducing the incidence of falciparum malaria.
Nerly Shirère Gampio Gueye +7 more
doaj +1 more source
Analysis of malaria associated genetic traits in Cabo Verde, a melting pot of European and sub Saharan settlers [PDF]
, 2009 Malaria has occurred in the Cabo Verde archipelago with epidemic characteristics since its colonization. Nowadays, it occurs in Santiago Island alone and though prophylaxis is not recommended by the World Health Organization, studies have highlight the ...
Alves, Joana +10 more
core +1 more source
Molecular evidence of Plasmodium vivax infection in Duffy negative symptomatic individuals from Dschang, West Cameroon [PDF]
, 2017 Background: Plasmodium vivax infection is known to be rare in West/Central Africa, the most accepted explanation being the lack of expression of erythroid Duffy antigen in the local human populations.
De Santis, Riccardo +11 more
core +2 more sources
Rapid turnover of T cells in acute infectious mononucleosis.
, 2003 During acute infectious mononucleosis (AIM), large clones of Epstein-Barr virus-specific T lymphocytes are produced. To investigate the dynamics of clonal expansion, we measured cell proliferation during AIM using deuterated glucose to label DNA of ...
Asquith, Becca +9 more
core +1 more source
Prevalence of glucose-6-phosphate dehydrogenase deficiency and its association with Plasmodium falciparum infection among children in Iganga distric in Uganda [PDF]
, 2014 BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) is a metabolic enzyme involved in the pentose phosphate pathway, its especially important in red blood cell metabolism.
Denis Bwayo +3 more
core +1 more source
eLife, 2017 Glucose-6-phosphate dehydrogenase (G6PD) deficiency is believed to confer protection against Plasmodium falciparum malaria, but the precise nature of the protective effect has proved difficult to define as G6PD deficiency has multiple allelic variants ...
Geraldine M Clarke +77 more
doaj +1 more source
Wellcome Open Research, 2020 Safe access to the most effective treatment options for Plasmodium vivax malaria are limited by the absence of accurate point-of-care testing to detect glucose-6-phosphate dehydrogenase (G6PD) deficiency, the most common human genetic disorder.
Cindy S Chu +8 more
doaj +1 more source
PLoS Neglected Tropical Diseases, 2022 BackgroundPrimaquine and tafenoquine are the only licensed drugs that effectively kill the hypnozoite stage and are used to prevent Plasmodium vivax malaria relapse.
Kamonwan Chamchoy +5 more
doaj +1 more source
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study [PDF]
, 2018 Background: Human genetic factors are important determinants of malaria risk. We investigated associations between multiple candidate polymorphisms—many related to the structure or function of red blood cells—and risk for severe Plasmodium falciparum ...
Alexander, W Macharia +28 more
core +1 more source
Wellcome Open Research, 2020 Safe access to the most effective treatment options for Plasmodium vivax malaria are limited by the absence of accurate point-of-care testing to detect glucose-6-phosphate dehydrogenase (G6PD) deficiency, the most common human genetic disorder.
Cindy S Chu +8 more
doaj +1 more source