Results 71 to 80 of about 7,778 (203)

Hematological and Genetic Predictors of Daytime Hemoglobin Saturation in Tanzanian Children with and without Sickle Cell Anemia. [PDF]

, 2013
Low hemoglobin oxygen saturation (SpO2) is common in Sickle Cell Anemia (SCA) and associated with complications including stroke, although determinants remain unknown.
Cox, Sharon E, Kirkham, Fenella J, Makani, Julie, Newton, Charles R, Prentice, Andrew M   +4 more
core   +5 more sources

The Impact of Phenotypic and Genotypic G6PD Deficiency on Risk of Plasmodium vivax Infection: A Case-Control Study amongst Afghan Refugees in Pakistan [PDF]

PLoS Medicine, 2010
The most common form of malaria outside Africa, Plasmodium vivax, is more difficult to control than P. falciparum because of the latent liver hypnozoite stage, which causes multiple relapses and provides an infectious reservoir. The African (A-) G6PD (glucose-6-phosphate dehydrogenase) deficiency confers partial protection against severe P. falciparum.
Toby Leslie, Marnie Briceño, Ismail Mayan, Nasir Mohammed, Eveline Klinkenberg, Carol Hopkins Sibley, Christopher J M Whitty, Mark Rowland   +7 more
openaire   +4 more sources

Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants.

, 2009
Intermittent preventive treatment in infants (IPTi) is an effective and safe malaria control strategy. However, it remains unclear what antimalarials should be used to replace sulfadoxine-pyrimethamine (SP) when and where SP is no longer an effective ...
Cairns, Matthew, Gosling, Roly, Gesase, Samwel, Mosha, Jacklin, Greenwood, Brian, Chandramohan, Daniel   +5 more
core   +1 more source

Hybrids between Schistosoma mansoni and S. rodhaini : characterization by isoelectric focusing of six enzymes [PDF]

, 1989
Une étude par isoélectrofocalisation sur gels polyacrulamides à partir d'extraits de #S. mansoni$ (Guadeloupe) et #S. rodhaini$ (Burundi) et de leurs hybrides expérimentaux (première et deuxième générations) a été entreprise sur 6 systèmes enzymatiques ...
Brémond, Philippe, Rollinson, D., Théron, A.   +2 more
core   +1 more source

Wide range of G6PD activities found among ethnic groups of the Chittagong Hill Tracts, Bangladesh.

PLoS Neglected Tropical Diseases, 2020
The proportion of Plasmodium vivax malaria among all malarias is increasing worldwide. Treatment with 8-aminoquinolines remain the only radical cure.
Benedikt Ley, Mohammad Golam Kibria, Wasif Ali Khan, Sarah Auburn, Ching Swe Phru, Nusrat Jahan, Fatema Tuj Johora, Kamala Thriemer, Jenifar Quaiyum Ami, Mohammad Sharif Hossain, Ric N Price, Cristian Koepfli, Mohammad Shafiul Alam   +12 more
doaj   +1 more source

Duffy blood system and G6PD genetic variants in vivax malaria patients from Manaus, Amazonas, Brazil

Malaria Journal, 2022
Background Over a third of the world’s population is at risk of Plasmodium vivax-induced malaria. The unique aspect of the parasite’s biology and interactions with the human host make it harder to control and eliminate the disease.
Natália S. Ferreira, Jéssica Lorena S. Mathias, Sérgio Roberto L. Albuquerque, Anne Cristine G. Almeida, Ana C. Dantas, Fernanda C. Anselmo, Emerson S. Lima, Marcus Vinicius G. Lacerda, Paulo A. Nogueira, Rajendranath Ramasawmy, Marilda S. Gonçalves, José P. Moura Neto   +11 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Females of HbAS genotype have reduced concentration of the malaria protective deoxyhemoglobin S than males. [PDF]

PLoS ONE, 2018
The quantity of the intra-erythrocytic deoxyhemoglobin S (Hb S) affects the level of protection against malaria and also the sickling phenomenon. This study reports on significantly lower concentration of Hb S in females than males.
John N Waitumbi, Carolyne M Kifude, Carol W Hunja, Bernhards R Ogutu   +3 more
doaj   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Clinical Significance of UGT1A1 Genetic Analysis in Chinese Neonates with Severe Hyperbilirubinemia

Pediatrics and Neonatology, 2016
Neonatal hyperbilirubinemia is common in Asia, and the importance of genetically determined conditions has been recently recognized. The aim of this study was to assess the clinical utility of genetic testing in Chinese neonates with severe ...
Hui Yang, Qian Wang, Lei Zheng, Xiang-bin Zheng, Min Lin, Xiao-Fen Zhan, Li-Ye Yang   +6 more
doaj   +1 more source