Results 111 to 120 of about 19,960,264 (249)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
“El interés superior del niño, niña y adolescentes como sujetos de derechos”. [PDF]
El presente trabajo tiene por objetivo abordar la temática grupos vulnerables y en contexto de vulnerabilidad. Se consideran grupos en situación de vulnerabilidad a las niñas, los niños y adolescentes (NNA en adelante) en situación de calle, los ...
Vidotto, Melanie Ayelen
core
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
"Priorizando el Vínculo Afectivo: El Interés Superior del Niño en los Procesos de Adopción según la Corte Suprema de Justicia de la Nación Argentina" [PDF]
El fallo bajo análisis “G., A. C. y otro s/ guarda con fines de adopción”, dictado por la Corte Suprema de Justicia de la Nación, en adelante CSJN, el 20 de abril de 2023, presenta relevancia porque implica un pronunciamiento acerca del principio de ...
Lobo Murtagh, Santiago Andrés
core
STAR ProtocolsSummary: Poly(ADP-ribose) polymerase 1 (PARP1) is a crucial DNA repair protein and a target of PARP inhibitors (PARPi), which suppress its catalytic activity while also altering its association with damaged chromatin. Here, we present a live-cell imaging
Petar-Bogomil Kanev +4 more
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Valoración del interés superior del adolescente el régimen de comunicación. [PDF]
Ante una realidad que presenta desafíos sociales, los niños, niñas y adolescentes necesitan el reconocimiento de derechos y garantías que les corresponden por ley; el interés superior del niño es una de las garantías más importantes del nuevo paradigma ...
Fernandez, Patricia Noemi
core
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
“El aborto legal ante la pretensión paterna: entre el principio de autonomía y los derechos del no nacido” [PDF]
Fallo seleccionado: “Cámara de Apelación Civil y Comercial Trenque Lauquen. Juzgado de origen: Juzgado de Paz Letrado de Guaminí. Autos: “B., C. G. c/ B., J. B. s/ medidas precautorias (art. 232 del CPCC)”. Expte.: -93809”.
Martina, Gustabo Rodrigo
core
Biological Therapy for Moderate-to-Severe Psoriasis: A 5-Year Analysis of Patients from Lithuania
MedicinaBackground and Objectives: Biological therapy is widely used to treat moderate-to-severe psoriasis. This study aimed to assess the real-world effectiveness and drug survival of biologic treatment in patients with moderate-to-severe psoriasis.
Elada Indrisiunaite +3 more
doaj +1 more source