Results 11 to 20 of about 11,803,234 (178)

Neuropathophysiological potential of Guillain-Barré syndrome anti-ganglioside-complex antibodies at mouse motor nerve terminals [PDF]

, 2011
Objectives:  Anti-ganglioside antibodies are present in approximately half of Guillain–Barré syndrome (GBS) patients. Recently, it has been shown that a considerable proportion of these patients has serum antibodies against antigenic epitopes formed by a
Susumu Kusunoki, Tio-Gillen, Anne P., Plomp, J.J., Kusunoki, Susumu, Tio-Gillen, A.P., Willison, H.J., Broos, Ludo A.M., Ueda, M., Mark L. Kuijf, Ludo A. M. Broos, Kuijf, Mark L., Jacobs, B.C., Greenshields, Kay N., Jacobs, Bart C., Zitman, F.M.P., Hugh J. Willison, Anne P. Tio-Gillen, Masami Ueda, Kuijf, M.L., Jaap J. Plomp, Kusunoki, S., Greenshields, K.N., Plomp, Jaap J., Femke M. P. Zitman, Broos, L.A.M., Kay N. Greenshields, Ken-ichi Kaida, Willison, Hugh J., Bart C. Jacobs, Kaida, Ken Ichi, Kaida, K.I., Ueda, Masami, Zitman, Femke M.P.   +32 more
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Neu3 sialidase-mediated ganglioside conversion is necessary for axon regeneration and is blocked in CNS axons [PDF]

, 2014
This work was supported by the Medical Research Council, the Christopher and Dana Reeve Foundation, the John and Lucille van Geest Foundation, the Henry Smith Charity, the Commonwealth and Overseas scholarships, and the Hinduja Cambridge Trust.PNS axons ...
Cheah, Menghon, Dotti, Carlos G, Andrews, Melissa R., Andrews, Melissa Renee, Kappagantula, Sunil, Abad-Rodriguez, Jose', Abad-Rodriguez, José, Fawcett, James W   +7 more
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Heterogeneity of detergent-insoluble membranes from human intestine containing caveolin-1 and ganglioside G_M1 [PDF]

American Journal of Physiology-Gastrointestinal and Liver Physiology, 2000
In intestinal epithelia, cholera and related toxins elicit a cAMP-dependent chloride secretory response fundamental to the pathogenesis of toxigenic diarrhea. We recently proposed that specificity of cholera toxin (CT) action in model intestinal epithelia may depend on the toxin's cell surface receptor ganglioside GM1.
K, Badizadegan, B L, Dickinson, H E, Wheeler, R S, Blumberg, R K, Holmes, W I, Lencer   +5 more
openaire   +2 more sources

Total ganglioside ablation at mouse motor nerve terminals alters neurotransmitter release level [PDF]

, 2010
Neuronal membrane gangliosides, forming a large family of sialylated glycosphingolipids, have been hypothesized to play important roles in synaptic transmission.
Furukawa, K., Plomp, J.J., Todorov, B., Willison, H.J., Zitman, F.M.P.   +4 more
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Concentrations of Ganglioside Type M1 and Immunoglobulin G in Colostrum Are Inversely Related to Bacterial Infection at Early Lactation in Cows [PDF]

Journal of Dairy Science, 2008
The levels of IgG and ganglioside type M1 in the colostrum of cows and heifers were analyzed to examine their utility in predicting acquisition of intramammary infection (IMI) during the first weeks postpartum. In general, high levels of IgG and ganglioside type M1 in cows were associated with lower new incidence of IMI, and linear discriminate ...
G, Leitner, O, Krifucks, S, Jacoby, Y, Lavi, N, Silanikove   +4 more
openaire   +2 more sources

Avaliação do emprego do GM1 após lesão medular experimental em ratos Evaluando el uso de GM1 después de lesión experimental de médula espinal en ratones Evaluation of the use of GM1 after experimental spinal cord injury in rats

Coluna/Columna, 2011
OBJETIVO: Avaliar a eficácia do GM1, administrado por via intraperitoneal, após lesão medular experimental em ratos. MÉTODOS: Foram utilizados 20 ratos da raça Wistar machos, adultos jovens, com média de idade de 20 semanas, pesando em torno de 350 g ...
Fabiano Inácio de Souza, Tarcísio Eloy Pessoa Barros Filho, Alexandre Fogaça Cristante   +2 more
doaj   +1 more source

Neuromuscular synaptic transmission in aged ganglioside-deficient mice [PDF]

, 2011
Gangliosides are sialylated glycosphingolipids that are present in high density on neuronal membranes, especially at synapses, where they are assumed to play functional or modulating roles.
Todorov, Boyan, Furukawa, Keiko, Furukawa, K., Plomp, J.J., Verschuuren, Jan J., Willison, H.J., Furukawa, Koichi, Plomp, Jaap J., Jacobs, B.C., Todorov, B., Willison, Hugh J., Jacobs, Bart C., Zitman, F.M.P., Verschuuren, J.J., Zitman, Femke M.P.   +14 more
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pH-dependent formation of membranous cytoplasmic body-like structure of ganglioside G(M1)/bis(monoacylglycero)phosphate mixed membranes. [PDF]

, 2007
International audienceMembrane structures of the mixtures of ganglioside G(M1) and endosome specific lipid, bis (monoacylglycero) phosphate (BMP, also known as lysobisphosphatidic acid) were examined at various pH conditions by freeze-fracture electron ...
Sugimoto, Ichiro, Kobayashi, Toshihide, Takahashi, Hiroshi, Ito, Kazuki, Makino, Asami, Fujisawa, Tetsuro, Matsuo, Hirotami, Hashimoto, Yasuhiro, Hayakawa, Tomohiro, Murate, Motohide   +9 more
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Purified human liver acid β-d-galactosidases possessing activity towards G(M1)-ganglioside and lactosylceramide [PDF]

Biochemical Journal, 1977
Our studies with purified human liver acid beta-D-galactosidases (EC 3.2.1.23) indicate that 4-methylumbelliferyl beta-D-galactosidase and G(M1)-ganglioside beta-D-galactosidase activities are identical with lactosylceramidase II activity. Evidence for this includes co-purification of all enzyme activities by affinity chromatography to yield a single ...
A L, Miller, R G, Frost, J S, O'Brien
openaire   +2 more sources

Photochemical labeling of human erythrocyte membrane proteins with radioiodinated 4-azidosalicylic acid derivatives of G(M3), G(D3), G(M1), and FucG(M1) gangliosides.

Acta Biochimica Polonica, 1998
Photoreactive gangliosides of high specific radioactivity may prove useful for studies on glycosphingolipid functions. We prepared 4-azidosalicylic acid (ASA) acylated derivatives of GM3, GD3, GM1, and FucGM1 gangliosides (gangliosides-ASA). Gangliosides-ASA were characterized by their TLC mobility, UV spectra, carbohydrate composition, and digestion ...
T, Pacuszka, M, Panasiewicz
openaire   +3 more sources