Results 201 to 210 of about 830,364 (264)

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

The roles of G protein-coupled receptor kinase 2 in renal diseases. [PDF]

J Cell Mol Med
Du J, Wu X, Ni L.
europepmc   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

The G Protein-Coupled Receptor GPR56 Is an Inhibitory Checkpoint for NK Cell Migration. [PDF]

J Immunol
Palacios D, Majhi RK, Szabo EK, Clement D, Lachota M, Netskar H, Penna L, Krokeide SZ, Vincenti M, Kveberg L, Malmberg KJ.   +10 more
europepmc   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

To activate a G protein-coupled receptor permanently with cell surface photodynamic action in the gastrointestinal tract. [PDF]

World J Gastroenterol
Cui ZJ.
europepmc   +1 more source

Takeda G protein-coupled receptor 5 (TGR5): an attractive therapeutic target for aging-related cardiovascular diseases. [PDF]

Front Pharmacol
He Y, Liu S, Zhang Y, Zuo Y, Huang K, Deng L, Liao B, Zhong Y, Feng J.   +8 more
europepmc   +1 more source

Artificial Intelligence: A New Tool for Structure-Based G Protein-Coupled Receptor Drug Discovery. [PDF]

Biomolecules
Chung J, Hahn H, Flores-Espinoza E, Thomsen ARB.   +3 more
europepmc   +1 more source

Leucine-rich repeat-containing G protein-coupled receptor 4 promotes proliferation, invasion and migration, and inhibits apoptosis in non-small cell lung cancer cells. [PDF]

Oncol Lett
Duan X, Liu X, Shan Y, Zhou S, Lou M, Gao Z, Yuan K.   +6 more
europepmc   +1 more source

The G protein-coupled receptor GPR89A is a novel potential therapeutic target to overcome cisplatin resistance in NSCLC Calu1 cells. [PDF]

FEBS J
Guler Kara H, Dogan E, Bozok V, Aktan C, Cakiroglu E, Eroglu Z, Aygunes Jafari D, Korkmaz KS, Senturk S, Kosova B.   +9 more
europepmc   +1 more source