Results 231 to 240 of about 1,031,574 (396)

The Structural Evolution of a P2Y-like G-protein-coupled Receptor [PDF]

, 2003
Angela Schulz, Torsten Schöneberg
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Fine-Tuning of the Neuropeptide Y1 G Protein-Coupled Receptor by the Tryptophan^6.48 "Toggle Switch". [PDF]

J Am Chem Soc
Voitel M, Pankonin M, Vogel A, Leitner K, Kaiser A, Huster D, Hildebrand PW, Smith AA.   +7 more
europepmc   +1 more source

The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6

Nature, 2016
A. Küffer, A. Lakkaraju, Amit Mogha, Sarah C Petersen, Kristina Airich, C. Doucerain, Rajlakshmi Marpakwar, Pamela Bakirci, Assunta Senatore, Arnaud Monnard, C. Schiavi, M. Nuvolone, Bianka L. Grosshans, S. Hornemann, F. Bassilana, Kelly R. Monk, A. Aguzzi   +16 more
semanticscholar   +1 more source

Integrated On-chip Photodetection of Intracellular Calcium in Response to the Activation of G-protein Coupled Receptors

, 2012
S. A. M. Martins, G. Moulas, João R. C. Trabuco, Gabriel A. Monteiro, V. Chu, J. P. Conde, D.M.F. Prazeres   +6 more
openalex   +1 more source

Known regulators of nitric oxide synthase and arginase are agonists at the human G‐protein‐coupled receptor GPRC6A [PDF]

, 2006
B. C. Christiansen, Petrine Wellendorph, Hans Bräuner‐Osborne   +2 more
openalex   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

The Drosophila G protein-coupled receptor, GulpR, is essential for lipid mobilization in response to nutrient-limitation. [PDF]

PLoS Genet
Barraza D, Ding X, Findley L, Wang Z, Jugder BE, Watnick PI.   +5 more
europepmc   +1 more source

The Diverse Roles of Arrestin Scaffolds in G Protein–Coupled Receptor Signaling

Pharmacological Reviews, 2017
Y. Peterson, L. Luttrell
semanticscholar   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source