Results 171 to 180 of about 426,123 (306)

Kinase Activity Is Not Required for G Protein-Coupled Receptor Kinase 4 Restraining mTOR Signaling during Cilia and Kidney Development.

J Am Soc Nephrol, 2023
Gerhards J, Maerz LD, Matthees ESF, Donow C, Moepps B, Premont RT, Burkhalter MD, Hoffmann C, Philipp M.   +8 more
europepmc   +1 more source

Endothelin receptor B enhances liver injury and pro-inflammatory responses by increasing G-protein-coupled receptor kinase-2 expression in primary biliary cholangitis. [PDF]

Sci Rep, 2022
Xu G, Gong Y, Lu F, Wang B, Yang Z, Chen L, Min J, Cheng C, Jiang T.   +8 more
europepmc   +1 more source

Threonine 180 Is Required for G-protein-coupled Receptor Kinase 3- and β-Arrestin 2-mediated Desensitization of the μ-Opioid Receptor in Xenopus Oocytes

, 2001
Jeremy Celver, Janet Lowe, Abraham Kovoor, Vsevolod V. Gurevich, Charles Chavkin   +4 more
openalex   +1 more source

Involvement of γ protein kinase C in estrogen‐induced neuroprotection against focal brain ischemia through G protein‐coupled estrogen receptor [PDF]

, 2005
Shigeto Hayashi, Takehiko Ueyama, Taketoshi Kajimoto, Keiko Yagi, Eiji Kohmura, Naoaki Saito   +5 more
openalex   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

G-protein-coupled receptor kinase 4 causes renal angiotensin II type 2 receptor dysfunction by increasing its phosphorylation. [PDF]

Clin Sci (Lond), 2022
Zhang F, Lei L, Huang J, Wang W, Su Q, Yan H, Chen C, Zheng S, Ren H, Li Z, Jose PA, Hu Y, Si L, Zeng C, Yang J.   +14 more
europepmc   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

GPER Enhances Chronic Burn Pain via PKC-Mediated Mu-Opioid Receptor Phosphorylation in the Rostral Ventromedial Medulla

Journal of Pain Research
Xunxi Zhu,1,2 Yajun Zhang,1,2 Qiqi Zhang,1,2 Zhongjun Zhang1,2 1Department of Anesthesiology, Affiliated Hospital of Jiangnan University, Wuxi, People’s Republic of China; 2Wuxi Medical School, Jiangnan University, Wuxi, People’s Republic of ...
Zhu X, Zhang Y, Zhang Q, Zhang Z
doaj  

The role of G protein-coupled receptor kinase 4 in cardiomyocyte injury after myocardial infarction. [PDF]

Eur Heart J, 2021
Li L, Fu W, Gong X, Chen Z, Tang L, Yang D, Liao Q, Xia X, Wu H, Liu C, Tian M, Zeng A, Zhou L, Jose PA, Chen K, Wang WE, Zeng C.   +16 more
europepmc   +1 more source

Suppression of G-protein–Coupled Receptor Kinase 3 Expression Is a Feature of Classical GBM That Is Required for Maximal Growth [PDF]

, 2011
B. Mark Woerner, Jingqin Luo, Kristin R. Brown, Erin Jackson, Sonika Dahiya, Paul S. Mischel, Jeffrey Benovic, David Piwnica‐Worms, Joshua B. Rubin   +8 more
openalex   +1 more source