Results 251 to 260 of about 396,098 (353)

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

G Protein-coupled Receptor Kinase 5 Regulates β1-Adrenergic Receptor Association with PSD-95 [PDF]

, 2002
Liaoyuan A. Hu, Wei Chen, Richard T. Premont, Mei Cong, Robert J. Lefkowitz   +4 more
openalex   +1 more source

Characterization of a hyperphosphorylated variant of G protein-coupled receptor kinase 5 expressed in E. coli. [PDF]

Protein Expr Purif, 2020
Beyett TS, Chen Q, Labudde EJ, Krampen J, Sharma PV, Tesmer JJG.   +5 more
europepmc   +1 more source

Rapid Signaling of Estrogen in Hypothalamic Neurons Involves a Novel G-Protein-Coupled Estrogen Receptor that Activates Protein Kinase C [PDF]

, 2003
Jian Qiu, Martha A. Bosch, Sandra C. Tobias, David K. Grandy, Thomas S. Scanlan, Oline K. Rønnekleiv, Martin J. Kelly   +6 more
openalex   +1 more source

Biofabrication of a Filtration Barrier by Integrating Electrospun Membranes and Flow in a Glomerular Co‐Culture

Advanced Healthcare Materials, EarlyView.
An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni, Anna Rederer, Vladimir Stepanenko, Frank Würthner, Philipp Stahlhut, Jürgen Groll, Mario Schiffer, Taufiq Ahmad, Janina Müller‐Deile   +8 more
wiley   +1 more source

Species-Specific Differences in Expression of G-Protein-Coupled Receptor Kinase (GRK) 7 and GRK1 in Mammalian Cone Photoreceptor Cells: Implications for Cone Cell Phototransduction

, 2001
Ellen R. Weiss, M. H. Ducceschi, Thierry Horner, A. Li, Christopher M. Craft, Shoji Osawa   +5 more
openalex   +2 more sources

Protein Kinase A and G Protein-coupled Receptor Kinase Phosphorylation Mediates β-1 Adrenergic Receptor Endocytosis through Different Pathways [PDF]

, 2003
Antonio Rapacciuolo, Shayela Suvarna, Liza Barki‐Harrington, Louis M. Luttrell, Mei Cong, Robert J. Lefkowitz, Howard A. Rockman   +6 more
openalex   +1 more source

Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum, Abhirami Thumsi, Kara Dunn, Lindsey Druschel, Sierra Chimene, David Flores Prieto, Amberlyn Simmons, Shivani Mantri, Arezoo Esrafili, Srivatsan J. Swaminathan, Mytreyi Trivedi, Shreya Anandan, Crystal Willingham, Alondra Davila, Sahil Inamdar, Joslyn L. Mangal, Abhirami P. Suresh, Niveda M. Kasthuri, Madan Mohan Chandra Sekhar Jaggarapu, Nicole Appel, Taravat Khodaei, Nathan D. Ng, Alison Sundem, Sanmoy Pathak, George Bjorklund, Jason Newbern, Jeffrey Capadona, Sarah E. Stabenfeldt, Abhinav P. Acharya   +28 more
wiley   +1 more source

G-Protein-Coupled Receptor Kinase-Interacting Protein 1 (GIT1) Promotes Head and Neck Squamous Cell Carcinoma Metastases via Activating the PI3K/AKT/mTOR Signal Pathway.

Comput Math Methods Med, 2022
Xu R, Xu R, Wang Y, Wang W, Jiang L, Gong S.   +5 more
europepmc   +1 more source

Role of G Protein-coupled Receptor Kinase 4 and ॆ-Arrestin 1 in Agonist-stimulated Metabotropic Glutamate Receptor 1 Internalization and Activation of Mitogen-activated Protein Kinases [PDF]

, 2003
Luisa Iacovelli, Lorena Salvatore, Loredana Capobianco, Antonietta Picascia, Eliana Barletta, Marianna Storto, Stefania Mariggiò, Michele Sallese, Antonio Porcellini, Ferdinando Nicoletti, Antonio De Blasi   +10 more
openalex   +1 more source