Results 271 to 280 of about 426,123 (306)

Probiotic‐Based Materials as Living Therapeutics

Advanced Materials, EarlyView.
Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio, Graham J. Day, Manuel Salmeron‐Sanchez   +2 more
wiley   +1 more source

G Protein-Coupled Receptor Kinase 2 (GRK2) as a Potential Therapeutic Target in Cardiovascular and Metabolic Diseases. [PDF]

Front Pharmacol, 2019
Murga C, Arcones AC, Cruces-Sande M, Briones AM, Salaices M, Mayor F.   +5 more
europepmc   +1 more source

The First Review on Nano‐Agricultural Applications of MXene and MBene‐Based Materials for Plant‐Immunoengineering, Controlled Protection, and Inducing Biostimulation Mechanisms

Advanced Materials, EarlyView.
MXene and MBene nanomaterials show significant potential in addressing critical challenges in biomedicine, applied biology, agriculture, and the environment. From a nano‐agricultural perspective, this relatively young field has witnessed emerging advances towards applications for plant‐immunoengineering, biostimulation, and controlled delivery ...
Alireza Rafieerad, Ahmad Amiri, Maik Böhmer, Soofia Khanahmadi   +3 more
wiley   +1 more source

MicroRNA-760 acts as a tumor suppressor in gastric cancer development via inhibiting G-protein-coupled receptor kinase interacting protein-1 transcription. [PDF]

World J Gastroenterol, 2019
Ge L, Wang Y, Duan QH, Liu SS, Liu GJ.
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Loss of dynamic regulation of G protein-coupled receptor kinase 2 by nitric oxide leads to cardiovascular dysfunction with aging.

Am J Physiol Heart Circ Physiol, 2020
Lieu M, Traynham CJ, de Lucia C, Pfleger J, Piedepalumbo M, Roy R, Petovic J, Landesberg G, Forrester SJ, Hoffman M, Grisanti LA, Yuan A, Gao E, Drosatos K, Eguchi S, Scalia R, Tilley DG, Koch WJ.   +17 more
europepmc   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Peptide Coacervates with Metal–Phenolic Membranes Modulate Glucose Metabolism and Enhance Cancer Immunotherapy

Advanced Materials, EarlyView.
Peptide coacervates encapsulated with interferon‐α and membranized with metal–phenolic networks (PC‐IFNα@MPNs) are designed to reprogram glucose competition between tumor and cytotoxic T cells. This metabolic modulation enhances immunotherapy by suppressing tumor glycolysis and boosting T cell effector function.
Xin Zheng, Shiqiong Lei, Yiwei Zeng, Lian Chen, Jingqu Chen, Wei Fu, Yu Chen, Xinping Hu, Jing Wang, Meiyuan Jin, Zhichen Liu, Xiaofang Dai, Lei Liu, Wenshan He, Jiajing Zhou, Zhixing Lin, Frank Caruso, Jinghua Ren   +17 more
wiley   +1 more source

The Bionic Interface: Considering the Material Mediated Electrical Stimulation of Stem Cells

Advanced Materials, EarlyView.
Electrical stimulation directs stem cell fate in tissue engineering. Cellular responses are influenced by membrane properties, intrinsic cell state, material charge‐transport characteristics, and the applied electrical signal. Additionally, a material’s ability to inject, store, and redistribute charge further modulates these responses.
Kaiwen Zhang, Daniel De Maria, Mercyjayapriya Jebakumar, James Collins, Kate E. Fox, Peter C. Sherrell, Amy Gelmi   +6 more
wiley   +1 more source

Lithium‐Charged Gold Nanoparticles: A New Powerful Tool for Lithium Delivery and Modulation of Glycogen Synthase Kinase 3 Activity

Advanced Materials, EarlyView.
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba, Giulia Puliatti, Domenica Donatella Li Puma, Bruno Bandiera, Beatrice Cannata, Maria Elena Marcocci, Nicolina Castagno, Irene Contento, Salvatore Impemba, Mariarosa Scognamiglio, Rocco Di Girolamo, Vincenzo Naddeo, Patrizia Canton, Carmine Capacchione, Laura Sposito, Martina Albini, Francesco Pastore, Silvia Baroni, Alfonso Grassi, Claudio Grassi, Roberto Piacentini   +20 more
wiley   +1 more source