Results 151 to 160 of about 425,489 (192)

Regulation of cellular oxidative stress and apoptosis by G protein-coupled receptor kinase-2; The role of NADPH oxidase 4. [PDF]

Cell Signal, 2016
Theccanat T, Philip JL, Razzaque AM, Razzaque AM, Ludmer N, Li J, Xu X, Akhter SA.   +7 more
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Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors. [PDF]

J Med Chem, 2016
Waldschmidt HV, Homan KT, Cruz-Rodríguez O, Cato MC, Waninger-Saroni J, Larimore KM, Cannavo A, Song J, Cheung JY, Kirchhoff PD, Koch WJ, Tesmer JJ, Larsen SD.   +12 more
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G-protein-coupled receptor kinase 2 and endothelial dysfunction: molecular insights and pathophysiological mechanisms. [PDF]

J Smooth Muscle Res, 2015
Taguchi K, Matsumoto T, Kobayashi T.
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Phenotypic regulation of the sphingosine 1-phosphate receptor miles apart by G protein-coupled receptor kinase 2. [PDF]

Biochemistry, 2015
Burczyk M, Burkhalter MD, Blätte T, Matysik S, Caron MG, Barak LS, Philipp M.   +6 more
europepmc   +1 more source

Opsin 3 and 4 mediate light-induced pulmonary vasorelaxation that is potentiated by G protein-coupled receptor kinase 2 inhibition.

Am J Physiol Lung Cell Mol Physiol, 2018
Barreto Ortiz S, Hori D, Nomura Y, Yun X, Jiang H, Yong H, Chen J, Paek S, Pandey D, Sikka G, Bhatta A, Gillard A, Steppan J, Kim JH, Adachi H, Barodka VM, Romer L, An SS, Shimoda LA, Santhanam L, Berkowitz DE.   +20 more
europepmc   +1 more source

Retraction: G protein-coupled receptor kinase-2 is a novel regulator of collagen synthesis in adult human cardiac fibroblasts. [PDF]

J Biol Chem, 2015
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Kinase-dependent and kinase-independent functions of G-protein-coupled receptor kinase 2 (GRK2)

, 2012
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G-protein-coupled receptor kinases in cardiovascular conditions: focus on G-protein-coupled receptor kinase 2, a gain in translational medicine

Biomarkers in Medicine, 2009
With increasing knowledge of the regulatory mechanisms of G-protein-coupled receptor signaling in heart physiology, many studies have focused on the role of this system in cardiovascular disease. In recent years, scientists have moved their attention from the receptors to their regulatory proteins: the G-protein-coupled receptor kinases.
IACCARINO, GUIDO, CAMPANILE, ALFONSO
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Regulation of G protein-coupled receptor kinase 2

2002
Publisher Summary G protein-coupled receptor kinase 2 (GRK2) was originally termed a “β-adrenergic receptor kinase” (βARK) because it was purified as a kinase of the adrenergic β 2 receptor, and the adrenergic β 2 receptor was the only known substrate of GRK2. GRK2 is now known to phosphorylate different kinds of G protein-coupled receptors (GPCRs),
Tatsuya, Haga, Kazuko, Haga, Kimihiko, Kameyama, Hirofumi, Tsuga, Norihiro, Yoshida   +4 more
openaire   +2 more sources