Results 131 to 140 of about 356,759 (248)

Quantitative approaches for studying G protein-coupled receptor signalling and pharmacology

Abigail Pearce, Theo Redfern-Nichols, E. J. Wills, Matthew Rosa, Iga Manulak, Claudia Sisk, Xianglin Huang, Peace Atakpa‐Adaji, David L. Prole, Graham Ladds   +9 more
openalex   +1 more source

Constitutively active orphan G protein-coupled receptors through the lenses of cryo-electron microscopy. [PDF]

J Biol Chem
Argerich J, Muñoz-Reyes D, Val-García ID, García-Nafría J.   +3 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Design of Gut-Restricted Thiazolidine Agonists of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5)

, 2018
Tao Chen, Nicholas William Reich, Noah Bell, Patricia D. Finn, David Rodríguez, Jill Kohler, Kenji Kozuka, Limin He, Andrew Spencer, Dominique Charmot, Marc Navre, Christopher W. Carreras, Samantha Koo-McCoy, Jocelyn Tabora, Jeremy S. Caldwell, Jeffrey Jacobs, Jason G. Lewis   +16 more
openalex   +1 more source

Insights into the structural dynamics of the secretin family (class B1) G protein-coupled receptors. [PDF]

J Biol Chem
Liu T, Naidoo NR, Agyemang E, Lamichhane R.   +3 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Expression Analysis of Retinal G Protein-coupled Receptor and its Correlation with Regulation of the Balance between Proliferation and Aberrant Differentiation in Cutaneous Squamous Cell Carcinoma

Jianglong Feng, Wei Zhang, Wen Zeng, Xian Dong, Yu Wang, Yangguang Gu, Yinghua Lan, Wenxiu Yang, Hongguang Lü   +8 more
openalex   +2 more sources

G protein-coupled receptors: pivotal hubs in gastric cancer malignancy-from multidimensional crosstalk to precision therapeutics. [PDF]

J Transl Med
Qin R, Fan X, Huang Y, Duan Y, Wang H.
europepmc   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Multi-faceted roles of β-arrestins in G protein-coupled receptors endocytosis [PDF]

Junke Liu, Xue Li, Magalie A. Ravier, Asuka Inoue, Julia Drube, Carsten Hoffmann, Eric Trinquet, Elodie Dupuis, Laurent Prézeau, Jean‐Philippe Pin, Philippe Rondard   +10 more
openalex   +1 more source