Results 141 to 150 of about 356,759 (248)

Self-cleavage of the GAIN domain of adhesion G protein-coupled receptors requires multiple domain-extrinsic factors. [PDF]

Nat Commun
Chung YK, Ihling CH, Zielke L, Mathiasen S, Sinz A, Langenhan T.   +5 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Double-edged role of G protein-coupled estrogen receptor 1 in breast cancer prognosis: an analysis of 167 breast cancer samples and online data sets

, 2016
Fan Yang, Zhi-min Shao
openalex   +2 more sources

G-Protein-Coupled Receptors in Chronic Kidney Disease Induced by Hypertension and Diabetes. [PDF]

Cells
Tang H, Li K, Shi Z, Wu J.
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Biased agonism of G protein-coupled receptors as a novel strategy for osteoarthritis therapy. [PDF]

Bone Res
Meng X, Qin L, Wang X.
europepmc   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Immunodetection of selected pancreatic hormones under intragastric administration of apelin-13, a novel endogenous ligand for an angiotensin-like orphan G-protein coupled receptor, in unweaned rats

Sylwia Szymańczyk, Katarzyna Kras, Cezary Osiak-Wicha, M. Kapica, Iwona Puzio, Hanna Antushevich, Atsukazu Kuwahara, Ikuo Kato, Marcin B. Arciszewski   +8 more
openalex   +1 more source

Alternative Splicing of G Protein–Coupled Receptors: Relevance to Pain Management

, 2020
Folabomi A. Oladosu, William Maixner, Andrea G. Nackley   +2 more
openalex   +1 more source

G Protein–Coupled Receptor Kinase 6 Deficiency Promotes Angiogenesis, Tumor Progression, and Metastasis [PDF]

, 2013
Sandeep K. Raghuwanshi, Nikia Smith, Elizabeth Rivers, Ariel J. Thomas, Natalie Sutton, Yuhui Hu, Somnath Mukhopadhyay, Xiaoxin Chen, TinChung Leung, Ricardo M. Richardson   +9 more
openalex   +1 more source