Results 361 to 370 of about 807,055 (385)

G protein—coupled receptor kinases

Cell, 1993
G protein‐coupled receptor kinases (GRKs) constitute a family of six mammalian serine/threonine protein kinases that phosphorylate agonist-bound, or activated, G protein‐coupled receptors (GPCRs) as their primary substrates. GRK-mediated receptor phosphorylation rapidly initiates profound impairment of receptor signaling, or desensitization.
openaire   +3 more sources

Molecular signatures of G-protein-coupled receptors

Nature, 2013
A. Venkatakrishnan, X. Deupí, G. Lebon, C. Tate, G. Schertler, G. Schertler, M. Babu   +6 more
semanticscholar   +1 more source

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

Nature, 1996
H. Daub, F. Weiss, C. Wallasch, A. Ullrich   +3 more
semanticscholar   +1 more source

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

Nature, 1999
Norbert Prenzel, Esther Zwick, H. Daub, M. Leserer, Reimar Abraham, C. Wallasch, A. Ullrich   +6 more
semanticscholar   +1 more source

[19] Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors

, 1995
J. Ballesteros, H. Weinstein
semanticscholar   +1 more source

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

Nature, 1996
I. Dikič, G. Tokiwa, S. Lev, S. Courtneidge, J. Schlessinger   +4 more
semanticscholar   +1 more source

G-Protein-Coupled Receptors

2006
S.B. Liggett, D.W. McGraw
openaire   +1 more source

Structure and Function of G Protein Coupled Receptors

Pharmaceutical Research, 1990
J. Lameh, R. Cone, S. Maeda, M. Philip, M. Corbani, L. Nádasdi, J. Ramachandran, Graham M. Smith, W. Sadee   +8 more
semanticscholar   +1 more source

Heterotrimeric G protein activation by G-protein-coupled receptors

Nature reviews. Molecular cell biology, 2008
W. Oldham, H. Hamm
semanticscholar   +1 more source

Mechanisms of signalling and biased agonism in G protein-coupled receptors

Nature reviews. Molecular cell biology, 2018
D. Wootten, D. Wootten, A. Christopoulos, M. Marti-Solano, M. Babu, P. Sexton, P. Sexton   +6 more
semanticscholar   +1 more source