Results 221 to 230 of about 21,426,917 (362)

G protein-coupled receptor-mediated renal fibrosis: a key focus on kidney disease drug development. [PDF]

Front Pharmacol
Wang H, Yang M, Liu X, Fan J, Wang C.
europepmc   +1 more source

Immunoglobulin G is a platelet alpha granule-secreted protein. [PDF]

, 1985
James N. George, S Saucerman, Shirley P. Levine, Linda K. Knieriem, D F Bainton   +4 more
openalex   +1 more source

Assembly of a GPCR-G Protein Complex

Cell, 2019
Yang Du, N. M. Duc, S. Rasmussen, D. Hilger, X. Kubiak, Liwen Wang, J. Bohon, H. Kim, M. Wegrecki, Awuri P Asuru, K. Jeong, Jeongmi Lee, M. Chance, D. Lodowski, B. Kobilka, K. Chung   +15 more
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Role of G-protein-coupled receptor kinase 4 on the dysfunction of renal Mas receptor in hypertension. [PDF]

PLoS One
Chen L, Chen J, Wan J, Shao M, Chen C, Zheng S, Zhang F, Yang J.   +7 more
europepmc   +1 more source

The Diverse Roles of Arrestin Scaffolds in G Protein–Coupled Receptor Signaling

Pharmacological Reviews, 2017
Y. Peterson, L. Luttrell
semanticscholar   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Constitutively active orphan G protein-coupled receptors through the lenses of cryo-electron microscopy. [PDF]

J Biol Chem
Argerich J, Muñoz-Reyes D, Val-García ID, García-Nafría J.   +3 more
europepmc   +1 more source

Further evidence for a phospholipase C-coupled G protein in hamster fibroblasts. Induction of inositol phosphate formation by fluoroaluminate and vanadate and inhibition by pertussis toxin.

, 1987
S Paris, Jacques Pouysségur
openalex   +1 more source

High-Resolution Crystal Structure of an Engineered Human β2-Adrenergic G Protein–Coupled Receptor

Science, 2007
V. Cherezov, D. Rosenbaum, M. Hanson, S. Rasmussen, Foon Sun Thian, T. S. Kobilka, Hee-Jung Choi, P. Kuhn, W. Weis, B. Kobilka, R. Stevens   +10 more
semanticscholar   +1 more source