Results 251 to 260 of about 5,959,864 (346)

Regulation of the orphan G-protein-coupled receptor GPRC5B by MLC1 and the cell adhesion molecule GlialCAM in megalencephalic leukoencephalopathy. [PDF]

J Biol Chem
Pont-Espinós G, Pla-Casillanis A, Ferigle L, Alonso-Gardón M, González-Subías M, Elorza-Vidal X, Gaitán-Peñas H, Errasti-Murugarren E, Chevigne A, López-Hernández T, Ciruela F, Estévez R.   +11 more
europepmc   +1 more source

G protein coupling and regulation of metabotropic glutamate receptor 6.

, 2010
Liantian Tian
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

CD Molecules Nomenclature 2025: Antibody Validation and Expression Profiling of Immune System G Protein-Coupled Receptors. [PDF]

Eur J Immunol
Fernández-Calles J, Kužílková D, Hedin F, Bakardjieva-Mihaylova V, Škvárová Kramarzová K, van Zelm MC, Cosma A, Kalina T, Engel P, Human Cell Differentiation Molecules (HCDM) organization.   +9 more
europepmc   +1 more source

Epidermal growth factor-mediated signaling of G(i)-protein to activation of phospholipases in rat-cultured hepatocytes.

, 1993
Lijun Yang, Anna Marie Camoratto, György Baffy, Satish R. Raj, David R. Manning, John Williamson   +5 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Structural insights into hormone recognition and G-protein coupling of the urotensin-II receptor. [PDF]

J Biol Chem
Gao T, You C, Cao Y, Xu X, Yuan Q, Shen S, Xu HE, Duan J.   +7 more
europepmc   +1 more source

Multi-faceted roles of β-arrestins in G protein-coupled receptors endocytosis [PDF]

Junke Liu, Xue Li, Magalie A. Ravier, Asuka Inoue, Julia Drube, Carsten Hoffmann, Eric Trinquet, Elodie Dupuis, Laurent Prézeau, Jean‐Philippe Pin, Philippe Rondard   +10 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Type-1 Cannabinoid Receptor Promiscuous Coupling: Computational Insights into Receptor-G Protein Interaction Dynamics. [PDF]

Int J Mol Sci
Berghella A, Stepniewski TM, Sabatucci A, Lopez-Balastegui M, Nowicki K, Dufrusine B, Selent J, Dainese E.   +7 more
europepmc   +1 more source