Results 261 to 270 of about 5,882,179 (311)

G Protein Selectivity in Dopamine Receptors is Determined before GDP Release. [PDF]

Biochemistry
Tawfeeq C, Hilibrand AS, Smith JS, Portillo J, Kruse AC, Abrol R.   +5 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

G Protein-Coupled Receptor 30 Attenuates Neuronal Pyroptosis Induced by Subarachnoid Hemorrhage. [PDF]

Mediators Inflamm
Peng J, Hu X, He J, Xia Y.
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Structural insight into the self-activation and G-protein coupling of P2Y2 receptor. [PDF]

Cell Discov
Lan B, Zhang S, Chen K, Dai S, Fei J, Gao K, Sun X, Lin B, Liu X.   +8 more
europepmc   +1 more source

G protein-coupled receptor of plants and its function in signal transduction

, 2012
Shuishan Song
openalex   +1 more source

eLife assessment: Visualization of endogenous G proteins on endosomes and other organelles

Felix Campelo
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Self-cleavage of the GAIN domain of adhesion G protein-coupled receptors requires multiple domain-extrinsic factors. [PDF]

Nat Commun
Chung YK, Ihling CH, Zielke L, Mathiasen S, Sinz A, Langenhan T.   +5 more
europepmc   +1 more source

Glycosilation reaction models and the role of Madagascar periwinkle (Catharanthus roseus CU G. Don)' S leaves infusion as protein damage inhibitor

, 2015
Rizky Taufan Firdaus
openalex   +1 more source