Estabilidade de cultivares de girassol no nordeste brasileiro: safra 2010. [PDF]
O objetivo deste trabalho foi averiguar a adaptabilidade e a estabilidade de cultivares de girassol quando avaliadas em diferentes ambientes do Nordeste brasileiro para fins de recomendação daquelas superiores. Os ensaios foram instalados no ano agrícola
CARVALHO, C. G. P. +8 more
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Inbreeding depression in castor bean (Ricinus communis L.) progenies. [PDF]
The purpose of this study was to investigate inbreeding depression (DE) in castor bean. From a population derived from the Guarani cultivar, 60 mother plants were sampled.
KRIEGER, M. +3 more
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Environmental stratification based on a 28 x 28 diallel of open-pollinated maize varieties. [PDF]
The objective of this study was to assess the representativeness of the test environments used by the maize breeding program of Embrapa in the first phase of genotype evaluation.
CARVALHO, H. W. L. de +9 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
GGE-Biplot Analysis of Grain Yield of Faba Bean Genotypes in Southern Ethiopia [PDF]
A Genotype x Environment (GxE) interaction study was conducted in Southern Ethiopia in 2007 and 2008 using 16 faba bean genotypes in a randomized complete block design with three replications.
Fekadu Gurmu, Ersulo Lire, Asrat Asfaw, Fitsum Alemayehu, Yeyis Rezene, Daniel Ambachew
doaj
Particle distributions in approximately 10(13) - 10(16) eV air shower cores at mountain altitude and comparison with Monte Carlo simulations [PDF]
Photographs of 521 shower cores in an array of current-limited spark (discharge) chambers at Sacramento Peak (2900m above sea level, 730 g /sq cm.), New Mexico, U.S.A., have been analyzed and the results compared with similar data from Leeds (80m above ...
Ash, A. G.
core +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source

