Results 151 to 160 of about 219,640 (255)

Acute Ethanol Exposure Inhibits GABA Uptake in Embryonic Chicken Retina. [PDF]

Neurochem Res
Damascena ACO, Abramov AK, Pinheiro L, Dos Santos Pereira M, Trindade P, Stipursky J, De Melo Reis RA, Kubrusly RCC.   +7 more
europepmc   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Effects of Foliar-Applied PAA@Mn₃O₄ Nanoparticles, Methyl Jasmonate, and γ-Aminobutyric Acid on Growth and Yield Performance of Sugar Beet (<i>Beta vulgaris</i> L.) Under Salt-Affected Conditions. [PDF]

Plants (Basel)
Zhang Z, Cao G, Yang L, Sun Y, Li G, Li N.   +5 more
europepmc   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Introducing a proline in the α1 M2-M3 linker relieves a molecular brake on channel activation in α1β2γ2 GABAA receptors. [PDF]

PLoS One
Desai NG, Garlapati P, Borghese CM, Goldschen-Ohm MP.   +3 more
europepmc   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Peripheral GABA Signaling in Metabolic Adaptation and Maladaptation. [PDF]

Int J Mol Sci
Saliu TP, Adetunji AO, Ogunsile JO, Popoola HO, Ikele CM, Miller SN, Oriakhi K, Diaz F, Karaganis SP.   +8 more
europepmc   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Antiepileptic Activity of Callicarpa kwangtungensis Chun Extract in Pilocarpine Induced Epilepsy in Mice via Modulating GABAergic and DAergic Transmission

BioResources
The effect of Callicarpa kwangtungensis Chun (CKC) was evaluated in Pilocarpine (P350, 350 mg/kg)-induced epilepsy in mice. The behavioral patterns of experimental mice were investigated by the number of convulsed animals, survivors, after P350-induced ...
Shiqing Li, Meizhi Li, Rutong Wei, Huawen Liu, Erwei Hu, Zhibing Zhou   +5 more
doaj  

GABA as an Overlooked Mediator of Metformin Action: GABA-mediated Neuropsychiatric and Hepatoprotective Activities of Metformin. [PDF]

Ann Neurosci
Belayneh YM.
europepmc   +1 more source