Results 141 to 150 of about 219,640 (255)

Theta oscillations, epileptogenesis, and focal seizures in rodent models of mesial temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Theta oscillations (4–12 Hz) are a prominent network rhythm within hippocampal and parahippocampal structures. Driven by cholinergic and γ‐aminobutyric acidergic inputs originating from the medial septum, physiological theta gates network excitability to control spatial navigation, memory encoding, and sensorimotor integration during specific ...
Maxime Lévesque, Massimo Avoli
wiley   +1 more source

Satellite Glial Cells Synthesize and Release GABA to Activate Extrasynaptic GABA_A Receptors That Modulate Dorsal Root Ganglia Neuron Excitability. [PDF]

Glia
Jiménez-Barrios N, González-Ramírez R, Paz-Bermúdez FJ, Raya-Tafolla G, Vila JS, Felix R, Delgado-Lezama R, Garduño BF.   +7 more
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Astrocytes mediate the dopaminergic modulation of tonic GABAergic signaling in substantia nigra. [PDF]

Sci Adv
Simmons DV, Moreno-Ramos OA, Raj DDA, Kaganovsky K, Pamukcu A, Vrieler N, Tkatch T, Xie Z, de Sousa AIS, Zampese E, Ding J, Awatramani R, Wilson CJ, Surmeier DJ.   +13 more
europepmc   +1 more source

GABA-immunoreactive Dogiel type I neurones and their synaptic relations in myenteric ganglia of the guinea pig small intestine

, 1991
GABA-immunoreactive Dogiel type I neurones and their synaptic relations in myenteric ganglia of the guinea pig small ...
John Furness (13070439), S Pompolo (13752835)   +1 more
core  

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Foliar GR24 and γ-aminobutyric acid modulate redox signaling, root-system architecture, and mineral homeostasis in tellurite-stressed wheat (<i>Triticum aestivum</i> L.). [PDF]

Plant Signal Behav
Haider I, Rehman SU, Iqbal Z, Mahmood A, Zaheer A, Nadeem MY, Mubushar M, Tahir MU.   +7 more
europepmc   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Inhibitory neurotransmission in frontostriatal circuitry: implications for psychomotor and vegetative symptoms in depressive episodes. [PDF]

BMC Psychiatry
Steinholtz L, Persson J, Thörnblom E, Wall A, Lubberink M, Fällmar D, Bodén R.   +6 more
europepmc   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source