Results 241 to 250 of about 163,092 (297)

Experimental Parkinsonism induced by tetanus toxin injected into basal ganglia

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Local inhibitory circuits and long‐range inhibitory projections within the interconnected basal ganglia nuclei are critical for control of voluntary movement and pathophysiology of different extrapyramidal movement disorders.
Patrik Meglić, Petra Šoštarić, Davor Virag, Ana Knezović, Nikola Habek, Ornella Rossetto, Ivica Matak   +6 more
wiley   +1 more source

Evaluating parameter selection and analysis approaches on quality and reproducibility of functional MRS

Pasanta D, Lythgoe DJ, Puts NA.
europepmc   +1 more source

Inhibitory Effect of Fluralaner on GABA Receptor Subunit RDL of <i>Bactrocera dorsalis</i>. [PDF]

Insects
Zhou X, Chen G, Chen K, Xu Z, Qian J, Yan R, Chen B, Wu H, Chen M.   +8 more
europepmc   +1 more source

Polypharmacy in mice disrupts left ventricular function and structure and promotes proteome reorganisation in an age‐ and sex‐specific fashion

British Journal of Pharmacology, EarlyView.
Background and Purpose Most older people use polypharmacy (≥5 medications), particularly those with cardiovascular disease. The effects of polypharmacy on the cardiovascular system are not well described. We examined the effect of a chronic polypharmacy regimen on left ventricular (LV) function, structure and proteome in young and old mice of both ...
Trang Tran, Kevin Winardi, Scott P. Levick, Alexander Widiapradja, Gizem Gemikonakli, Susan E. Howlett, Matthew J. McKay, Mark P. Molloy, John Mach, Sarah N. Hilmer   +9 more
wiley   +1 more source

Molecular basis of human GABA transporter 3 inhibition. [PDF]

Nat Commun
Yadav R, Han GW, Gati C.
europepmc   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Neural excitation/inhibition imbalance and neurodevelopmental pathology in human copy number variant syndromes: a systematic review. [PDF]

J Neurodev Disord
Sylvester AL, Hensenne E, Ivanov D, Poser BA, Linden DEJ, van Amelsvoort T, Vingerhoets C.   +6 more
europepmc   +1 more source

A GLP‐1R/Y1 receptor/Y2 receptor triple agonist decreases fentanyl‐evoked dopamine release in the nucleus accumbens and attenuates fentanyl taking and seeking in rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Emerging literature indicates that simultaneously targeting glucagon‐like peptide‐1 receptors (GLP‐1Rs) and neuropeptide Y receptors (Y1/Y2) may represent a new pharmacotherapeutic approach to treating opioid use disorder (OUD).
Antonia Caffrey, Enzo Lavecchia, Kylie S. Chichura, Matthew R. Hayes, Robert P. Doyle, Heath D. Schmidt   +5 more
wiley   +1 more source

Mitigating effect of γ-aminobutyric acid and gibberellic acid on tomato plant cultivated in Pb-polluted soil. [PDF]

Sci Rep
Shoaib S, Iqbal RK, Ashraf H, Younis U, Rasool MA, Ansari MJ, Alarfaj AA, Alharbi SA.   +7 more
europepmc   +1 more source