Results 221 to 230 of about 346,715 (290)

Preclinical 1H MRS Study of a Porcine Model Shows Evidence and Mechanisms for Acute Neuronal Injury in Neonatal Cardiopulmonary Bypass (CPB) Surgery

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Congenital heart disease affects 1% of US births, with some infants requiring cardiothoracic surgery under cardiopulmonary bypass (CPB). Optimal surgical parameters to minimize neuronal injury are unknown. We used serial 1H MRS in a neonatal CPB porcine model to assess acute neuronal damage and associated injury mechanisms.
Aaron Omon, Meng Gu, Ralph Hurd, Kirk Riemer, Frank Hanley, Daniel Spielman   +5 more
wiley   +1 more source

Exogenous GABA regulates the growth traits, photosynthesis, antioxidant properties, and nitrogen metabolism in <i>Isatis indigotica</i> Fortune seedlings. [PDF]

Front Plant Sci
Cheng S, Fan P, He P, Mei K, Liu H, Sun K, Ren Y.   +6 more
europepmc   +1 more source

The Impact and Reliability of Tissue Segmentation on In Vivo Magnetic Resonance Spectroscopy Metabolite Quantification

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Quantification of metabolite concentrations using MRS requires tissue‐dependent signal corrections. Accurate estimation of voxel tissue composition is therefore essential. Commonly used brain tissue segmentation tools differ in their algorithms and implementation, potentially introducing variability in MRS‐derived concentration ...
Jessica Archibald, Kay Chioma Igwe, Antonia Kaiser, Karl Landheer, Jaimie Lee, John L. K. Kramer, Aaron T. Gudmundson, Helge J. Zöllner, Georg Oeltzschner, Candace C. Fleischer, Niklaus Zölch, Jamie Near, Mark Mikkelsen   +12 more
wiley   +1 more source

A transcriptomic resource for glial GABA-associated ASH neuronal aging and candidate pathways. [PDF]

Front Aging Neurosci
Al-Sheikh U, Cheng H, Bakrbaldawi AAA, He L, Chen D, Zhan R, Kang L, Zhang Y.   +7 more
europepmc   +1 more source

GABA+‐Edited Magnetic Resonance Spectroscopy Deep Learning Quality Assessment Framework

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Motivated by the need to improve GABA+‐edited magnetic resonance spectroscopy (MRS) quality, we developed a three‐module framework to improve transient averaging based on quality. We hypothesized that training a deep learning (DL) model to differentiate spectrum quality could improve transient averaging compared to traditional ...
Hanna Bugler, Roberto Souza, Ashley D. Harris   +2 more
wiley   +1 more source

Structural basis for selective inhibition of human GABA transporter GAT3. [PDF]

Nat Commun
Mortensen JS, Bavo F, Jensen MH, Pedersen APS, Storm JP, Pape T, Frølund B, Wellendorph P, Shahsavar A.   +8 more
europepmc   +1 more source

Identifying knowledge barriers to agroforestry adoption and co‐designing solutions to them

People and Nature, EarlyView.
Abstract Compared to monocultures, agroforestry can promote biodiversity, ecosystem functioning and climate resilience, whilst maintaining or enhancing production and profits. Despite this, uptake in temperate regions remains low. Knowledge gaps amongst land managers are a primary barrier to uptake, but little is known about which aspects of ...
Amelia S. C. Hood, Verena Scherfranz, Rosy E. Scholes, Erika Degani, Tom Staton, Alexa Varah, Lena Schaller, Alice L. Mauchline   +7 more
wiley   +1 more source