Results 201 to 210 of about 159,634 (258)

Integrating mechanistic models to decode the GnRH pulse generator in female mice. [PDF]

open access: yesJ Mol Endocrinol
Nechyporenko K   +5 more
europepmc   +1 more source

Relationship between brain metabolites and chronic pain mechanisms in knee osteoarthritis pre- and post-total knee replacement. [PDF]

open access: yesNeurobiol Pain
Leech SA   +14 more
europepmc   +1 more source

Astrocytes as GABA-ergic and GABA-ceptive Cells

Neurochemical Research, 2012
GABA (gamma-aminobutyric acid) is considered to be the major inhibitory neurotransmitter that is synthesized in and released from GABA-ergic neurons in the brain. However, recent studies have shown that not only neurons but astrocytes contain a considerable amount of GABA, which can be released and activate the receptors responsive to GABA. In addition,
Bo-Eun Yoon, Junsung Woo, C Justin Lee
exaly   +3 more sources

GABA Transporters and GABA-Transaminase as Drug Targets

Current Drug Target -CNS & Neurological Disorders, 2003
The fine-tuning and homeostatic balance of the GABAergic inhibitory tone in the central nervous system (CNS) is a prerequisite for controlling the excitatory neurotransmission. This principal mechanism for controlling excitation is inhibition which has been the topic of intensive research covering all known functional entities of the GABAergic synapse.
Alan, Sarup   +2 more
openaire   +2 more sources

Occurrence of GABA and GABA receptors in human spermatozoa

Molecular Human Reproduction, 1998
Gamma-aminobutyric acid (GABA) concentrations in seminal plasma and washed spermatozoa from normal donors were assessed by a sensitive radioreceptor assay, and were detectable in both fractions. Specific binding of [3H]-muscimol was shown to be dependent on protein concentration, temperature and incubation time.
M N, Ritta, J C, Calamera, D E, Bas
openaire   +2 more sources

GABA and GABA receptors in invertebrates

Seminars in Neuroscience, 1991
Abstract GABA is the major inhibitory transmitter at invertebrate synapses in both the central and peripheral nervous systems. The receptors for GABA are well characterised electrophysiologically in a wide variety of invertebrate organisms but their biochemical and pharmacological profiles are less well defined. In general invertebrate GABA receptors
openaire   +1 more source

Pharmacology of GABA

Clinical Neuropharmacology, 1982
GABA-ergic systems are involved in all the main functions of the brain. In most brain regions impairment of this system produces epileptic activity. GABA-mediated inhibitory function can be enhanced by drugs of at least seven different types. They act on the metabolism or synaptic release of GABA, or its reuptake into neurones of glia, or on various ...
openaire   +2 more sources

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