Results 211 to 220 of about 346,715 (290)

Acute fipronil toxicity in humans following intentional ingestion: a case report with favorable outcome from a resource-limited setting. [PDF]

Int J Emerg Med
Abebe AB, Ayenew DE, Asfaw SD.
europepmc   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Chloride homeostasis dysfunction drives hyperactivation of corticotropin-releasing factor-expressing neurons in the amygdala in stress-induced hypertension. [PDF]

J Clin Invest
Ma H, Zhang Y, Guo X, Zhao Q, Yang P, Liu Y, Guan Y, Wei Y, Ma H.   +8 more
europepmc   +1 more source

Convergence Deficits in Myoclonus‐Dystonia Point to Cerebellar Impairment

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Myoclonus‐dystonia (M‐D) is a monogenic movement disorder, with proposed cerebellar dysfunction. Vergence eye movement deficits, characteristics of degenerative cerebellar disease, have not been studied in M‐D. Cerebellar transcranial alternating current stimulation (tACS) is considered a potential therapeutic approach.
Skadi Gerkensmeier, Christina Bolte, Jan‐Ole Radecke, Feline Hamami, Andreas Sprenger, Christoph Helmchen, Robert Chen, Marcus Callister, Talyta Cortez Grippe, Christine Klein, Norbert Brüggemann, Tobias Bäumer, Alexander Münchau, Anne Weissbach   +13 more
wiley   +1 more source

Conditional Modeling of GNAO1 Disorder Dissociates Circuit Specific Contributions to Pathology and Rationalizes Ameliorative Strategies

Movement Disorders, EarlyView.
Abstract Background Neurodevelopmental disorders feature various symptoms that frequently include seizures and motor manifestations, but their attribution to disruptions of specific circuits and molecular alterations is notoriously hard to establish, which limits therapeutic interventions.
Gloria Brunori, Stefano Zucca, Colten K. Lankford, Yi‐Zhi Wang, Marianna Franco, Nina A. Alekseeva, Sevinj Ahmedova, Han My Van, Jeffrey N. Savas, Kirill A. Martemyanov   +9 more
wiley   +1 more source

Effects of <i>in vitro</i> fermentation of <i>Astragalus</i> polysaccharide on gut microbiota and neurotransmitter metabolites in patients with major depressive disorder. [PDF]

Front Psychiatry
Lin C, Mi YW, Zheng HW, Hou YB, Hu JQ, Mao JX, Dai N, Fu CL, Li XQ, Ji YX.   +9 more
europepmc   +1 more source

Effect of Water Suppression and Metabolite Cycling on Quantification of 1H MRS Spectra in the Human Brain at 3 Tesla

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose This study investigates the effect of VAPOR water suppression and metabolite cycling on metabolite quantification and macromolecules in proton magnetic resonance spectroscopy. Methods Single‐voxel semi‐LASER spectra (TR/TE = 3000/28 ms) and metabolite‐nulled spectra (macromolecules) were acquired in five healthy subjects in the ...
Dinesh K. Deelchand, Pierre‐Gilles Henry   +1 more
wiley   +1 more source

Thalamic GABA+ levels are negatively associated with neuropsychiatric symptoms in patients with insomnia. [PDF]

Front Hum Neurosci
Dai M, Hong H, Mao Y, Wang R, Jia Y, Xu D, Yan G.   +6 more
europepmc   +1 more source