Results 261 to 270 of about 163,092 (297)

Late emergence of pathological oscillatory activity in the retina of the Retinitis pigmentosa model RCS (Royal College of Surgeons) rat. [PDF]

PLoS One
Nruthyathi, Jung M, Wang J, Montes VR, Offenhäusser A, Willuweit A, Müller F.   +6 more
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Baclofen, a GABA_Breceptor agonist, impairs motor learning in healthy people and changes inhibitory dynamics in motor areas

Grigoras I, Geist E, Johnstone A, Clarke WT, Emir U, Nettekoven C, Levenstein JM, Capitao L, Stagg CJ.   +8 more
europepmc   +1 more source

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Does the GABA Shunt Regulate Cytosolic GABA?

Trends in Plant Science, 2020
The GABA shunt has long been known as a metabolic pathway that produces GABA in, and removes GABA from, the cytosol. There is no consensus regarding its function. The hypothesis presented here is that the GABA shunt regulates cytosolic GABA levels and GABA signaling.
Alan W. Bown, Barry J. Shelp
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GABA and GABA amide metabolism in the brain

Neurochemical Journal, 2012
We studied glutamine utilization and GABA formation in brain mitochondria from rats that were subjected to aluminum intoxication under conditions of activation or inhibition of phosphate-activated glutaminase (PAG). Phosphate did not influence the activities of rats intoxicated with aluminum. GABA formation from glutamine after inhibition of PAG with 6-
A. G. Vardanyan, R. G. Kamalyan
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GABA

2012
Publisher Summary γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian central nervous sys­tem (CNS). A growing body of evidence suggests a role for altered GABAergic function in neurological and psychiatric dis­orders of humans, primarily, related to the hyperexcitability.
Anouk M. van Loon, H. Steven Scholte, Simon van Gaal, Bjxf6rn J. J. van der Hoort, Victor A. F. Lamme   +4 more
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GABA Transporters and GABA-Transaminase as Drug Targets

Current Drug Target -CNS & Neurological Disorders, 2003
The fine-tuning and homeostatic balance of the GABAergic inhibitory tone in the central nervous system (CNS) is a prerequisite for controlling the excitatory neurotransmission. This principal mechanism for controlling excitation is inhibition which has been the topic of intensive research covering all known functional entities of the GABAergic synapse.
Orla M. Larsson, Alan Sarup, Arne Schousboe   +2 more
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Astrocytes as GABA-ergic and GABA-ceptive Cells

Neurochemical Research, 2012
GABA (gamma-aminobutyric acid) is considered to be the major inhibitory neurotransmitter that is synthesized in and released from GABA-ergic neurons in the brain. However, recent studies have shown that not only neurons but astrocytes contain a considerable amount of GABA, which can be released and activate the receptors responsive to GABA. In addition,
C. Justin Lee, Bo-Eun Yoon, Junsung Woo
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Occurrence of GABA and GABA receptors in human spermatozoa

Molecular Human Reproduction, 1998
Gamma-aminobutyric acid (GABA) concentrations in seminal plasma and washed spermatozoa from normal donors were assessed by a sensitive radioreceptor assay, and were detectable in both fractions. Specific binding of [3H]-muscimol was shown to be dependent on protein concentration, temperature and incubation time.
J C Calamera, M N Ritta, D E Bas
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