ABSTRACT Flavonoids are natural secondary metabolites of plants with a basic composition derived from polyphenols that can produce a plethora of different neurophysiological effects, some of which are relevant to anxiety disorders. As such, many flavonoids have been evaluated in behavioral screens in preclinical research on anxiolytics.
Jhennify Albuquerque Machado +7 more
wiley +1 more source
Neurometabolic profiles of autism spectrum disorder patients with genetic variants in specific neurotransmission and synaptic genes. [PDF]
Vilela J +10 more
europepmc +1 more source
Decision‐making in entrepreneurial teams with competing economic and noneconomic goals
Abstract Research Summary How should decision‐making be organized in entrepreneurial teams pursuing competing economic and noneconomic goals? Using a computational model, we examine how four archetypical decision‐making structures—unanimous approval, individual autonomy, majority voting, and lead entrepreneur—shape the performance of entrepreneurial ...
Jeroen Neckebrouck, Thomas Zellweger
wiley +1 more source
GLP-1 selectively enhances tonic GABA<sub>A</sub> receptor-mediated currents in mouse dentate gyrus granule cells of the ventral hippocampus. [PDF]
Netsyk O, Korol SV, Birnir B, Jin Z.
europepmc +1 more source
Abstract Research Summary This study draws on the behavioral theory of the firm and a duality perspective to investigate the impact of founders' focus on academic goals on the financial performance of academic spin‐offs (ASOs)—a specific type of hybrid venture. We theorize that such relationship follows an inverse U‐shaped curve and is moderated by the
Tommaso Minola +4 more
wiley +1 more source
State-dependent reactivity of anterior cingulate cortex neurochemistry and downstream autonomic arousal in intrusive thinking. [PDF]
Schettino M +8 more
europepmc +1 more source
Sensory Responses in Autistic Individuals—A Narrative Review
Caption—Atypical sensory processing in Autism Spectrum Disorder. ABSTRACT The first clinical descriptions of autism from the late 1960s mentioned sensory dysregulation as one of the commonly reported findings among autistic individuals, yet, it was not until 2013 that they were included as part of the core symptoms of autism spectrum disorder (ASD) in ...
Anisha Kaundinya, Sowmyashree Mayur Kaku
wiley +1 more source
Targeting GABA signaling in the tumor microenvironment: implications for immune cell regulation and immunotherapy resistance. [PDF]
Zhao Y, Xu J, Yang K, Bao L.
europepmc +1 more source
Insight into the bioactivity and action mode of betulin, a candidate aphicide from plant metabolite, against aphids. [PDF]
Wang J +9 more
europepmc +1 more source
Toward Imaging of the GABA Transporter Type 1 In Vivo: Quantitative Evaluation of 4 Novel PET Radiotracers in Nonhuman Primates. [PDF]
Gravel P +14 more
europepmc +1 more source

