Results 1 to 10 of about 171,989 (360)

Intra-accumbens baclofen, but not muscimol, increases second order instrumental responding for food reward in rats. [PDF]

open access: yesPLoS ONE, 2012
Stimulation of either GABA(A) or GABA(B) receptors within the nucleus accumbens shell strongly enhances food intake in rats. However the effects of subtype-selective stimulation of GABA receptors on instrumental responses for food reward are less well ...
Kim G T Pulman   +2 more
doaj   +16 more sources

GABAA and GABAB Receptors Mediate GABA-Induced Intracellular Ca2+ Signals in Human Brain Microvascular Endothelial Cells

open access: yesCells, 2022
Numerous studies recently showed that the inhibitory neurotransmitter, γ-aminobutyric acid (GABA), can stimulate cerebral angiogenesis and promote neurovascular coupling by activating the ionotropic GABAA receptors on cerebrovascular endothelial cells ...
Sharon Negri   +8 more
doaj   +1 more source

Pharmacological Effect of GABA Analogues on GABA-ϱ2 Receptors and Their Subtype Selectivity

open access: yesLife, 2022
GABAϱ receptors are distinctive GABAergic receptors from other ionotropic GABAA and metabotropic GABAB receptors in their pharmacological, biochemical, and electrophysiological properties. Although GABA-ϱ1 receptors are the most studied in this subfamily,
Moawiah M. Naffaa   +3 more
doaj   +1 more source

Functional modifications of acid-sensing ion channels by ligand-gated chloride channels. [PDF]

open access: yesPLoS ONE, 2011
Together, acid-sensing ion channels (ASICs) and epithelial sodium channels (ENaC) constitute the majority of voltage-independent sodium channels in mammals. ENaC is regulated by a chloride channel, the cystic fibrosis transmembrane conductance regulator (
Xuanmao Chen   +3 more
doaj   +1 more source

Gamma‐aminobutyric acid (GABA) can affect physiological processes in preimplantation embryos via GABAA and GABAB receptors

open access: yesReproductive Medicine and Biology, 2023
Purpose Several widely used substances (e.g., some therapeutics or food supplements) can act on gamma‐aminobutyric acid (GABA) receptors, and we investigated whether the activation of these receptors could affect the preimplantation embryo.
Veronika Kovaříková   +7 more
doaj   +1 more source

Expression of GABAergic receptors in mouse taste receptor cells. [PDF]

open access: yesPLoS ONE, 2010
Multiple excitatory neurotransmitters have been identified in the mammalian taste transduction, with few studies focused on inhibitory neurotransmitters.
Margaret R Starostik   +4 more
doaj   +1 more source

GABAB Receptors Tonically Inhibit Motoneurons and Neurotransmitter Release from Descending and Primary Afferent Fibers

open access: yesLife, 2023
Motoneurons receive thousands of excitatory and inhibitory synapses from descending tracts and primary afferent fibers. The excitability of these neurons must be precisely regulated to respond adequately to the requirements of the environment.
Ximena Delgado-Ramírez   +6 more
doaj   +1 more source

Computational prediction of MicroRNAs targeting GABA receptors and experimental verification of miR-181, miR-216 and miR-203 targets in GABA-A receptor

open access: yesBMC Research Notes, 2012
Background GABA receptors are well known as the inhibitory receptors in the central nervous system and are also found in peripheral tissues. We have previously shown that GABA receptors are involved in lung development and fluid homeostasis. However, the
Zhao Chunling   +5 more
doaj   +1 more source

Endoplasmic reticulum sorting and kinesin-1 command the targeting of axonal GABAB receptors. [PDF]

open access: yesPLoS ONE, 2012
In neuronal cells the intracellular trafficking machinery controls the availability of neurotransmitter receptors at the plasma membrane, which is a critical determinant of synaptic strength.
Viviana Valdés   +7 more
doaj   +1 more source

GABAA-ρ Receptors in the CNS: Their Functional, Pharmacological, and Structural Properties in Neurons and Astroglia

open access: yesNeuroglia, 2023
Gamma-aminobutyric acid (GABA) is known as the main inhibitory transmitter in the central nervous system (CNS), where it hyperpolarizes mature neurons through activation of GABAA receptors, pentameric complexes assembled by combination of subunits (α1–6,
Abraham Rosas-Arellano   +3 more
doaj   +1 more source

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