Results 141 to 150 of about 171,989 (360)

Modulation of GABA_A receptor activity by alphaxalone [PDF]

, 1987
Glen A. Cottrell, Jeremy J. Lambert, John A. Peters   +2 more
openalex   +1 more source

Resting‐state functional connectivity changes with microburst vagus nerve stimulation therapy

Epilepsia Open, EarlyView.
Abstract Objective Microburst vagus nerve stimulation (μVNS) may reduce seizure frequency in drug‐resistant epilepsy (DRE) via targeted thalamic plasticity. We prospectively investigated the role of thalamic resting‐state functional connectivity (rsFC) in μVNS effects and hypothesized a relationship between thalamic rsFC and long‐term seizure frequency
Jane B. Allendorfer, Rodolphe Nenert, Elhum Shamshiri, Giovanni Ranuzzi, Jason Begnaud, Ryan Verner, Jerzy P. Szaflarski, for the Microburst Study Group, Rebecca O’Dwyer, Michael Macken, Blake Newman, Cornelia Drees, Danielle McDermott, Lesley Kaye, Mesha Gay Brown, Muhammad Zafar, William Tatum, Selim Benbadis, Pegah Afra, Zeenat Jaisani, Kristl Vonck   +20 more
wiley   +1 more source

Phosphorylation of γ-aminobutyrate (GABA)/benzodiazepine receptors by cyclic AMP-dependent protein kinase [PDF]

, 1989
Ewen F. Kirkness, C F Bovenkerk, Tetsufumi Ueda, Anthony J. Turner   +3 more
openalex   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

GABA Receptors Can Depolarize the Neuronal Membrane Potential via Quantum Tunneling of Chloride Ions: A Quantum Mathematical Study. [PDF]

Cells, 2022
Nawafleh S, Qaswal AB, Suleiman A, Alali O, Zayed FM, Al-Adwan MAO, Bani Ali M.   +6 more
europepmc   +1 more source

An arylaminopyridazine derivative of gamma-aminobutyric acid (GABA) is a selective and competitive antagonist at the GABAA receptor site. [PDF]

, 1985
J. P. Chambón, P. Feltz, Michel Héaulme, S. Restle, Rémy Schlichter, Kathleen Bizière, Camille G. Wermuth   +6 more
openalex   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

INFLUENCE OF CELLULAR TRANSPORT ON THE INTERACTION OF AMINO ACIDS WITH γ‐AMINOBUTYRIC ACID (GABA)‐RECEPTORS IN THE ISOLATED OLFACTORY CORTEX OF THE GUINEA‐PIG [PDF]

, 1980
David A. Brown, G.G.S. Collins, M. Galvan   +2 more
openalex   +1 more source

SCN1A gain of function effects in Dravet syndrome: Insights into clinical phenotypes and therapeutic implications

Epilepsia Open, EarlyView.
Abstract A large number of cases with Dravet syndrome (DS) has been attributed to SCN1A loss of function (LOF), whereas SCN1A gain‐of‐function (GOF) causes early infantile developmental and epileptic encephalopathy (EIDEE) and familial hemiplegic migraine 3.
Yoko Kobayashi Takahashi, Kenshiro Tabata, Shimpei Baba, Eri Takeshita, Noriko Sumitomo, Yuko Shimizu‐Motohashi, Takashi Saito, Eiji Nakagawa, Atsushi Ishii, Shinichi Hirose, Mitsuhiro Kato, Naomichi Matsumoto, Hirofumi Komaki, Ken Inoue   +13 more
wiley   +1 more source

Gama-aminobutyric acid (GABA) alleviates hepatic inflammation via GABA receptors/TLR4/NF-κB pathways in growing-finishing pigs generated by super-multiparous sows. [PDF]

Anim Nutr, 2022
Zhang S, Zhao J, Hu J, He H, Wei Y, Ji L, Ma X.   +6 more
europepmc   +1 more source