Results 181 to 190 of about 173,247 (311)

Efficacy and tolerability of fenfluramine with concomitant potassium bromide in patients with Dravet syndrome

Epilepsia Open, EarlyView.
Abstract Objective To assess the efficacy and tolerability of fenfluramine (FFA) with concomitant potassium bromide (BR) in patients with Dravet syndrome (DS). Methods This multicenter retrospective study, conducted within the German compassionate use program, analyzed BR doses and serum levels before and after FFA initiation, adverse events (AEs ...
Milka Pringsheim, Gerhard Kluger, Adam Strzelczyk, Susanne Schubert‐Bast, Thomas Mayer, Benjamin Glauche, Hiltrud Muhle, Michael Alber, Hartwig Spors, Tilmann Polster, Regina Trollmann, Gerhard Kurlemann, Markus Berndt, Kerstin A. Klotz   +13 more
wiley   +1 more source

Biochemical Properties of γ-Aminobutyric Acid(GABA) Receptor

, 1981
Kinya Kuriyama, Yoshihisa Ito, Eiko Ueno, Chihiro Nishimura, Yukio Yoneda   +4 more
openalex   +1 more source

SCN1A gain of function effects in Dravet syndrome: Insights into clinical phenotypes and therapeutic implications

Epilepsia Open, EarlyView.
Abstract A large number of cases with Dravet syndrome (DS) has been attributed to SCN1A loss of function (LOF), whereas SCN1A gain‐of‐function (GOF) causes early infantile developmental and epileptic encephalopathy (EIDEE) and familial hemiplegic migraine 3.
Yoko Kobayashi Takahashi, Kenshiro Tabata, Shimpei Baba, Eri Takeshita, Noriko Sumitomo, Yuko Shimizu‐Motohashi, Takashi Saito, Eiji Nakagawa, Atsushi Ishii, Shinichi Hirose, Mitsuhiro Kato, Naomichi Matsumoto, Hirofumi Komaki, Ken Inoue   +13 more
wiley   +1 more source

Comparative analysis of isoxazoline activity on human and canine GABA receptors expressed in Xenopus oocytes. [PDF]

Parasit Vectors
Sager H, Sarr A, Kuntz E, Rufener L.
europepmc   +1 more source

Neurochemical studies on γ-aminobutyric acid(GABA) receptor.(XV) Pharmacological properties of purified GABAA/benzodiazepine receptor complex from bovine cerebral cortex and its co-purification with [35S]t-butylbicyclophosphorothionate binding site by benzodiazepine affinity column chromatography

, 1986
Junichi Taguchi, Kinya Kuriyama
openalex   +1 more source

Epilepsy and systemic autoimmune diseases: A bidirectional two‐sample Mendelian randomization study

Epilepsia Open, EarlyView.
Abstract Objective Epidemiological data indicates that individuals with epilepsy exhibit an elevated susceptibility to autoimmune disorders, and conversely, those with systemic autoimmune diseases (SAD) demonstrate a heightened predisposition to epilepsy.
Ruoshi Tian, Wenlong Yu, Jiaqing Hu, Yan Yang, Xirui He   +4 more
wiley   +1 more source

Differential Effects of Prenatal Poly I:C Exposure and Antipsychotics on NMDA/GABA Receptors and GSK3β-Mediated Signaling in the Dorsal Raphe Nucleus of Female Rats. [PDF]

Fundam Clin Pharmacol
Chen S, Lian J, Su Y, Deng C.
europepmc   +1 more source

Neurotransmitter signaling in white matter [PDF]

, 2014
Butt, Arthur M., Fern, Robert F., Matute, Carlos   +2 more
core   +1 more source

Exploring the long‐term effects of COVID‐19 in patients with epilepsy: A multicenter Italian observational study

Epilepsia Open, EarlyView.
Abstract Objective Coronavirus disease‐19 (COVID‐19), caused by SARS‐CoV‐2, has led to a global pandemic since December 2019. People with epilepsy (PwE) face higher risks of severe COVID‐19 outcomes and may be more vulnerable to long‐term neurological and psychiatric effects. Methods This multicenter, retrospective cohort study reviewed medical records
Fedele Dono, Mirella Russo, Giacomo Evangelista, Clarissa Corniello, Claudio Liguori, Carmen Calvello, Flavia Narducci, Catello Vollono, Stefano Sensi   +8 more
wiley   +1 more source

The Role of GABA Receptors in Anesthesia and Sedation: An Updated Review. [PDF]

CNS Drugs
Philip AB, Brohan J, Goudra B.
europepmc   +1 more source