Results 191 to 200 of about 171,989 (360)

Tics and Parkinson's Disease: Clinical and Pathophysiological Insights from a Rare Syndromic Association

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The coexistence of tics with Parkinson's disease (PD) is rare, as they often emerge at different ages, follow different trajectories and involve contrasting pathophysiological mechanisms related to dopamine availability and function in the brain. Cases We present 10 individuals with primary tic disorders who later developed PD.
Tarig Abkur, Alexandra Boogers, Talyta Grippe, David A. Isaacs, Irene A. Malaty, Renato P. Munhoz, Kailash P. Bhatia, Lauren A. Hart, Alfonso Fasano, Suneil Kalia, Anthony E. Lang, Christos Ganos   +11 more
wiley   +1 more source

Biochemical Properties of γ-Aminobutyric Acid(GABA) Receptor

, 1981
Kinya Kuriyama, Yoshihisa Ito, Eiko Ueno, Chihiro Nishimura, Yukio Yoneda   +4 more
openalex   +1 more source

Whether the Opsoclonus Myoclonus Syndrome Is Paraneoplastic or SARS‐CoV‐2–Related Can Be Clarified

IJU Case Reports, EarlyView.
Josef Finsterer
wiley   +1 more source

Comparative analysis of isoxazoline activity on human and canine GABA receptors expressed in Xenopus oocytes. [PDF]

Parasit Vectors
Sager H, Sarr A, Kuntz E, Rufener L.
europepmc   +1 more source

Neurochemical studies on γ-aminobutyric acid(GABA) receptor.(XV) Pharmacological properties of purified GABAA/benzodiazepine receptor complex from bovine cerebral cortex and its co-purification with [35S]t-butylbicyclophosphorothionate binding site by benzodiazepine affinity column chromatography

, 1986
Junichi Taguchi, Kinya Kuriyama
openalex   +1 more source

Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou, Prabesh Kanel, Miriam van Emde Boas, Stiven Roytman, Giulia Carli, Roger L. Albin, Nicolaas I. Bohnen   +6 more
wiley   +1 more source

The Role of GABA Receptors in Anesthesia and Sedation: An Updated Review. [PDF]

CNS Drugs
Philip AB, Brohan J, Goudra B.
europepmc   +1 more source

Pathophysiological Role of Primary Motor Cortex in Essential Tremor

Movement Disorders, EarlyView.
Abstract Background Essential tremor (ET) is one of the most prevalent movement disorders. However, the complete understanding of ET pathophysiology remains elusive. Objective To explore the pathophysiological role of primary motor cortex (M1) in ET, specifically exploring its neurophysiological changes and their correlation with voluntary motor ...
Daniele Birreci, Luca Angelini, Giulia Paparella, Davide Costa, Antonio Cannavacciuolo, Massimiliano Passaretti, Martina De Riggi, Simone Aloisio, Donato Colella, Andrea Guerra, Matteo Bologna   +10 more
wiley   +1 more source

Exploring the sedative properties of natural molecules from hop cones (Humulus lupulus) as promising natural anxiolytics through GABA receptors and the human serotonin transporter. [PDF]

Front Chem
Belal A, Elballal MS, Al-Karmalawy AA, Hassan AHE, Roh EJ, Ghoneim MM, Ali MAM, Obaidullah AJ, Alotaibi JM, Shaaban S, Elanany MA.   +10 more
europepmc   +1 more source

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications

Medicinal Research Reviews, EarlyView.
ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra, Zoltán Mucsi, Janez Ilaš, Petra Dunkel   +3 more
wiley   +1 more source