Results 31 to 40 of about 171,989 (360)

Role of GABA and its receptors in anti-adipogenesis in cultured adipocytes [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2020
Health benefits of GABA and GABA-enriched foods via anti-obesity activity have been demonstrated in animals. However, the functional roles of GABA especially as non-neurotransmitter in adipocytes have not been thoroughly clarified.
Kanittaporn Trisat, Saowalak Yomlar, Nanteetip Limpeanchob   +2 more
doaj   +1 more source

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica, Devin K. Binder, Meinrad Drexel, Chrysanthy Ikonomidou, Shilpa D. Kadam, Guenther Sperk, Christian Steinhäuser   +6 more
wiley   +1 more source

Stimulation of TM3 Leydig cell proliferation via GABA_A receptors: A new role for testicular GABA

Reproductive Biology and Endocrinology, 2004
The neurotransmitter gamma-aminobutyric acid (GABA) and subtypes of GABA receptors were recently identified in adult testes. Since adult Leydig cells possess both the GABA biosynthetic enzyme glutamate decarboxylase (GAD), as well as GABAA and GABAB ...
Krieger Annette, Thalhammer Andrea, Doepner Richard FG, Geigerseder Christof, Mayerhofer Artur   +4 more
doaj   +1 more source

The potential role of pancreatic γ-aminobutyric acid (GABA) in diabetes mellitus: A critical reappraisal

International Journal of Preventive Medicine, 2021
Background: Diabetes mellitus (DM) is an endocrine disorder characterized by hyperglycemia, polyuria, polydipsia, and glucosuria. γ-aminobutyric acid (GABA) is an inhibitory neurotransmitter in the central nervous system (CNS) of humans and other mammals.
Hayder M Al-Kuraishy, Nawar R Hussian, Marwa S Al-Naimi, Ali I Al-Gareeb, Farah Al-Mamorri, Ali K Al-Buhadily   +5 more
doaj   +1 more source

Insights into GABA receptor signalling in TM3 Leydig cells [PDF]

, 2005
gamma-Aminobutyric acid (GABA) is an emerging signalling molecule in endocrine organs, since it is produced by endocrine cells and acts via GABA(A) receptors in a paracrine/autocrine fashion.
Artur Mayerhofer, Behar TN, Ben Ari Y, Berman JA, Christof Geigerseder, Erdo SL, Frungieri MB, Fukura H, Gilon P, Haydar TF, Karl Föhr, Kriegstein AR, Lars Kunz, Lauder JM, Lee W, Leinekugel X, Malherbe P, Maric D, Mayerhofer A, Mayerhofer A, Mayerhofer A, Monica B. Frungieri, Owens DF, Owens DF, Ricardo S. Calandra, Richard F.G. Doepner, Ritta MN, Romi Raemsch, Silvia I. Gonzalez-Calvar   +28 more
core   +2 more sources

A companion to the preclinical common data elements and case report forms for in vivo rodent neuroimaging: A report of the TASK3‐WG3 Neuroimaging Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet, Riikka Immonen, Ofer Prager, Alon Friedman, Jens P. Bankstahl, David K. Wright, Terence J. O'Brien, Heidrun Potschka, Olli Gröhn, Neil G. Harris   +9 more
wiley   +1 more source

GABA potency at GABAA receptors found in synaptic and extrasynaptic zones

Frontiers in Cellular Neuroscience, 2012
The potency of GABA is vitally important for its primary role in activating GABAA receptors and acting as an inhibitory neurotransmitter. Although numerous laboratories have presented information, directly or indirectly, on GABA potency, it is often ...
Martin eMortensen, Bijal ePatel, Trevor G. Smart   +2 more
doaj   +1 more source

Effects of ethylenediamine – a putative GABA-releasing agent – on rat hippocampal slices and neocortical activity in vivo [PDF]

, 2010
The simple diamine diaminoethane (ethylenediamine, EDA) has been shown to activate GABA receptors in the central and peripheral nervous systems, partly by a direct action and partly by releasing endogenous GABA.
Addae, J.I., Lui, C., Stone, T.W.
core   +1 more source

Activation of the Rat α1β2ε GABA_A Receptor by Orthosteric and Allosteric Agonists

Biomolecules, 2022
GABAA receptors are a major contributor to fast inhibitory neurotransmission in the brain. The receptors are activated upon binding the transmitter GABA or allosteric agonists including a number of GABAergic anesthetics and neurosteroids.
Allison L. Germann, Ariel B. Burbridge, Spencer R. Pierce, Gustav Akk   +3 more
doaj   +1 more source

GABA receptors in a state of fear. [PDF]

Nat Neurosci, 2015
Our internal states can color our memories just as powerfully as the external environment. A study finds that hippocampal GABAA receptors and associated microRNAs are important for generating state-dependent contextual fear memories.
Holmes A, Chen A.
europepmc   +5 more sources