Structure‐Function Integration in 2D Hybrid Perovskite for Fast Neutron and Gamma Ray Discrimination
Advanced Science, EarlyView.Using an in situ seed‐assisted cooling method, large (28 × 7 × 3 mm3) (GABA)2PbBr4 single crystals are grown, featuring hydrogen‐rich organic layers and a dense PbBr4 framework. This architecture enables efficient γ‐ray absorption, fast‐neutron sensitivity, and clear n/γ pulse‐shape discrimination (FOM up to 1.74), highlighting its potential as a ...
Yingming Wang +15 more
wiley +1 more source
Fast detection of extrasynaptic GABA with a whole-cell sniffer
Frontiers in Cellular Neuroscience, 2014 Gamma-amino-butyric acid (GABA) is the main inhibitory transmitter of the brain. It operates by binding to specific receptors located both inside and outside synapses.
Rasmus Kordt Christensen +3 more
doaj +1 more source
GABABreceptors couple to Gαqto mediate increases in voltage‐dependent calcium current during development [PDF]
, 2015 Andrew S. Karls, Michelle Mynlieff
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M1 muscarinic acetylcholine receptor‐mediated inhibition of GABA release from striatal medium spiny neurons onto cholinergic interneurons [PDF]
, 2020 Etsuko Suzuki, Toshihiko Momiyama
openalex +1 more source
Animal Models and Experimental Medicine, EarlyView.The cumulative effect of EA analgesia is partially attributed to the activation of EA‐TRAPed cells in ACC. Multiple EA sessions and single EA sessions activated different neuronal populations in the ACC. The enhanced analgesic effect of multiple EA sessions may be attributed to an increase in the proportion of GABAergic neurons within the ACC. Abstract
Zi Guo +8 more
wiley +1 more source
Frontiers in PharmacologyIntroductionAlcohol use disorder (AUD) causes significant morbidity and mortality globally. Ethanol’s rewarding and reinforcing effects are attributed to activation of the mesolimbic dopamine system, increasing accumbal dopamine release. While activation
Davide Cadeddu +7 more
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Emerging neurotrophic role of GABAB receptors in neuronal circuit development
Frontiers in Cellular Neuroscience, 2013 The proper development of highly organized structures in the central nervous system is a complex process during which key events – neurogenesis, migration, growth, differentiation and synaptogenesis – have to take place in an appropriate manner to create
Jean-Luc eGaiarsa +3 more
doaj +1 more source
Effects of gestational haloperidol exposure on mRNA expressions related to glutamate and GABA receptors in offspring. [PDF]
IBRO Neurosci Rep, 2023 Kumon H +5 more
europepmc +1 more source
Back Again to the Future: A New Era for Cerebroprotection
Annals of Neurology, EarlyView.Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley +1 more source
Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice
Annals of Neurology, EarlyView.A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi +10 more
wiley +1 more source