Results 141 to 150 of about 1,283,132 (206)
Pharmacological chaperones restore proteostasis of epilepsy-associated GABAA receptor variants. [PDF]
Wang YJ +4 more
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GLP-1 selectively enhances tonic GABA<sub>A</sub> receptor-mediated currents in mouse dentate gyrus granule cells of the ventral hippocampus. [PDF]
Netsyk O, Korol SV, Birnir B, Jin Z.
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Brain Research Reviews, 1999
Recent advances in molecular biology and complementary information derived from neuropharmacology, biochemistry and behavior have dramatically increased our understanding of various aspects of GABAA receptors. These studies have revealed that the GABAA receptor is derived from various subunits such as alpha1-alpha6, beta1-beta3, gamma1-gamma3, delta ...
A K, Mehta, M K, Ticku
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Recent advances in molecular biology and complementary information derived from neuropharmacology, biochemistry and behavior have dramatically increased our understanding of various aspects of GABAA receptors. These studies have revealed that the GABAA receptor is derived from various subunits such as alpha1-alpha6, beta1-beta3, gamma1-gamma3, delta ...
A K, Mehta, M K, Ticku
openaire +2 more sources
Pharmacological modulation of GABAA receptors
Current Opinion in Pharmacology, 2021Ligand-gated ion channels are integral membrane proteins that activate through a change in conformation upon transmitter binding and were identified as key players of brain function. GABAA receptors are major inhibitory ligand-gated ion channels of this protein family.
Frédéric, Knoflach, Daniel, Bertrand
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Molecular Biology of the GABAA Receptor
1988The GABAA receptorreceptor is the major molecular site of the ubiquitous inhibitory acEivities of the brain, being present on the great majority of mammalian brain neurones (1). Electrophysiological studies and, especially, recent patch-clamp studies on cultured neurones (2,3) have established that at these sites GABA opens a chloride channel which is ...
Barnard, E. +9 more
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1996
Transmitter-gated ion channels are multisubunit membrane-spanning receptors that serve as rapid signal transduction devices regulating the flow of cations or anions through the cell membrane. Cell type—specific flexibility in neurotransmission is accomplished by a multiplicity of channel variants based on the combinatorial assembly of structurally ...
H. Mohler +5 more
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Transmitter-gated ion channels are multisubunit membrane-spanning receptors that serve as rapid signal transduction devices regulating the flow of cations or anions through the cell membrane. Cell type—specific flexibility in neurotransmission is accomplished by a multiplicity of channel variants based on the combinatorial assembly of structurally ...
H. Mohler +5 more
openaire +1 more source

